SuCComBase

Sulfur Containing Compound Database

SCC Gene Description

Gene name MYB28
AGI ID AT5G61420
Gene length 366
Uniprot ID Q9SPG2
Protein Name Transcription factor MYB28
Synonym PMG1
EC number N/A
Entrez Gene 836263
Refseq mrna NM_180910
Refseq protein NP_851241
Function In a screen for the trans-activation potential of various transcription factors toward GSL biosynthetic genes; MYB28 was identified as a positive regulator of aliphatic methionine-derived GSLs. The content of aliphatic GSLs as well as transcript levels of aliphatic GSL biosynthetic genes were elevated in gain-of-function mutants and decreased in MYB28 RNAi knock-down mutants (Gigolashvili et al. 2007)
Group GSL transcription factor / Camalexin biosynthesis
Reference Burow et al. (2015); Gigolashvili et al. (2007); Stotz et al. (2011); Sønderby et al. (2007); Sønderby et al. (2010)
Organism AGI ID Gene Name Protein Name Identity E-Value Description

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

79

0.00E+00

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

77

0.00E+00

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

60

6.00E-128

Papaya

AT5G61420

MYB28

Transcription factor MYB28

50

1.00E-71

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

74

2.00E-69

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

74

2.00E-69

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

68

3.00E-68

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

72

2.00E-67

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

70

2.00E-67

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

73

3.00E-67

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

73

7.00E-67

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

70

7.00E-67

Papaya

AT5G61420

MYB28

Transcription factor MYB28

73

8.00E-67

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

69

1.00E-66

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

73

2.00E-66

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

72

3.00E-66

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

72

7.00E-66

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

71

1.00E-64

Papaya

AT5G61420

MYB28

Transcription factor MYB28

70

5.00E-63

Papaya

AT5G61420

MYB28

Transcription factor MYB28

70

7.00E-63

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

70

7.00E-63

Papaya

AT5G61420

MYB28

Transcription factor MYB28

69

7.00E-63

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

68

7.00E-63

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

70

1.00E-62

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

69

1.00E-62

Cabbage

AT5G61420

MYB28

Transcription factor MYB28

69

2.00E-62

Papaya

AT5G61420

MYB28

Transcription factor MYB28

68

9.00E-62

Papaya

AT5G61420

MYB28

Transcription factor MYB28

69

2.00E-61

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

70

4.00E-61

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

64

4.00E-59

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

62

1.00E-58

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

73

2.00E-58

Papaya

AT5G61420

MYB28

Transcription factor MYB28

64

2.00E-58

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

61

4.00E-58

Papaya

AT5G61420

MYB28

Transcription factor MYB28

64

1.00E-57

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

58

2.00E-57

Papaya

AT5G61420

MYB28

Transcription factor MYB28

60

5.00E-57

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

69

8.00E-57

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

53

2.00E-56

Papaya

AT5G61420

MYB28

Transcription factor MYB28

59

2.00E-56

Papaya

AT5G61420

MYB28

Transcription factor MYB28

59

3.00E-56

Papaya

AT5G61420

MYB28

Transcription factor MYB28

65

5.00E-56

Papaya

AT5G61420

MYB28

Transcription factor MYB28

70

1.00E-55

Papaya

AT5G61420

MYB28

Transcription factor MYB28

63

2.00E-55

Papaya

AT5G61420

MYB28

Transcription factor MYB28

60

3.00E-55

Papaya

AT5G61420

MYB28

Transcription factor MYB28

58

7.00E-55

Papaya

AT5G61420

MYB28

Transcription factor MYB28

63

1.00E-54

Papaya

AT5G61420

MYB28

Transcription factor MYB28

62

5.00E-54

Papaya

AT5G61420

MYB28

Transcription factor MYB28

63

5.00E-54

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

60

1.00E-53

Papaya

AT5G61420

MYB28

Transcription factor MYB28

59

3.00E-53

Papaya

AT5G61420

MYB28

Transcription factor MYB28

61

5.00E-53

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

61

8.00E-53

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

60

4.00E-52

Papaya

AT5G61420

MYB28

Transcription factor MYB28

62

5.00E-52

Papaya

AT5G61420

MYB28

Transcription factor MYB28

59

6.00E-52

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

55

1.00E-51

Papaya

AT5G61420

MYB28

Transcription factor MYB28

58

2.00E-51

Broccoli

AT5G61420

MYB28

Transcription factor MYB28

57

2.00E-51

Papaya

AT5G61420

MYB28

Transcription factor MYB28

62

6.00E-51

Papaya

AT5G61420

MYB28

Transcription factor MYB28

65

9.00E-51

GO ID Ontology GO Term Description

GO:0000981

MF

RNA polymerase II transcription factor activity, sequence-specific DNA binding

Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.

GO:0001135

MF

transcription factor activity, RNA polymerase II transcription factor recruiting

Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II

GO:0003677

MF

DNA binding

Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).

GO:0003700

MF

transcription factor activity, sequence-specific DNA binding

A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene in order to modulate transcription. Regulatory regions include promoter

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0006351

BP

transcription, DNA-templated

The cellular synthesis of RNA on a template of DNA.

GO:0006355

BP

regulation of transcription, DNA-templated

Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.

GO:0006357

BP

regulation of transcription from RNA polymerase II promoter

Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009625

BP

response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.

GO:0009682

BP

induced systemic resistance

A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling.

GO:0009739

BP

response to gibberellin

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gibberellin stimulus.

GO:0009751

BP

response to salicylic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.

GO:0009753

BP

response to jasmonic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.

GO:0010438

BP

cellular response to sulfur starvation

Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfur.

GO:0010439

BP

regulation of glucosinolate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0030154

BP

cell differentiation

The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable pha

GO:0043565

MF

sequence-specific DNA binding

Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.

GO:0044212

MF

transcription regulatory region DNA binding

Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a facto

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

Pubmed ID Authors Year Title Journal Description

25758208

Burow, M., Atwell, S., Francisco, M., Kerwin, R.E., Halkier, B.A. & Kliebenstein, D.J.

2015

The Glucosinolate Biosynthetic Gene AOP2 Mediates Feed-back Regulation of Jasmonic Acid Signaling in Arabidopsis

Mol Plant

17521412

Gigolashvili, T., Yatusevich, R., Berger, B., M?ller, C. & Fl?gge, U.-I.

2007

The R2R3-MYB transcription factor HAG1/MYB28 is a regulator of methionine-derived glucosinolate biosynthesis in Arabidopsis thaliana

Plant Journal

18094747

S?nderby, I.E., Hansen, B.G., Bjarnholt, N., Ticconi, C., Halkier, B.A. & Kliebenstein, D.J.

2007

A systems biology approach identifies a R2R3 MYB gene subfamily with distinct and overlapping functions in regulation of aliphatic glucosinolates

PLoS One

20303821

S?nderby, I.E., Geu-Flores, F. & Halkier, B.A.

2010

Biosynthesis of glucosinolates--gene discovery and beyond

Trends Plant Sci