SuCComBase

SCC Gene Description

Gene name	ASA1
AGI ID	AT5G05730
Gene length	595
Uniprot ID	P32068
Protein Name	Anthranilate synthase alpha subunit 1 chloroplastic
Synonym	WEI2
EC number	EC 4.1.3.27
Entrez Gene	830457
Refseq mrna	NM_120655
Refseq protein	NP_196192
Function	In RNA gel-blot analysis 35S-ATR1 displayed elevated accumulation of ATR1 and Trp gene transcripts including two Trp synthesis genes; ASA1 and TSB1 and three Trp secondary metabolism genes CYP79B2; CYP79B3; and CYP83B1. ASA1 encodes the catalytic alpha-subunit of anthranilate synthase the first committed enzyme of the Trp pathway and TSB1 encodes the Trp synthase beta-subunit activity that converts indole to Trp (Celenza et al. 2005)
Group	GSL core structure synthesis / Camalexin biosynthesis
Reference	Celenza et al. (2005); Schuhegger et al. (2007)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value	Description
Broccoli	AT5G05730	ASA1	Anthranilate synthase alpha subunit 1 chloroplastic	92	0.00E+00
Cabbage	AT5G05730	ASA1	Anthranilate synthase alpha subunit 1 chloroplastic	91	0.00E+00
Broccoli	AT5G05730	ASA1	Anthranilate synthase alpha subunit 1 chloroplastic	89	0.00E+00
Papaya	AT5G05730	ASA1	Anthranilate synthase alpha subunit 1 chloroplastic	70	0.00E+00
Cabbage	AT5G05730	ASA1	Anthranilate synthase alpha subunit 1 chloroplastic	72	0.00E+00
Cabbage	AT5G05730	ASA1	Anthranilate synthase alpha subunit 1 chloroplastic	74	0.00E+00
Papaya	AT5G05730	ASA1	Anthranilate synthase alpha subunit 1 chloroplastic	69	0.00E+00

GO ID	Ontology	GO Term	Description
GO:0000162	BP	tryptophan biosynthetic process	The chemical reactions and pathways resulting in the formation of tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid; tryptophan is synthesized from chorismate via anthranilate.
GO:0004049	MF	anthranilate synthase activity	Catalysis of the reaction: chorismate + L-glutamine = anthranilate + pyruvate + L-glutamate.
GO:0005950	CC	anthranilate synthase complex	A heterotetrameric enzyme complex made up of two components I and two components II. Catalyzes the formation of anthranilate, pyruvate and L-glutamate from chorismate and L-glutamine.
GO:0009507	CC	chloroplast	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
GO:0009570	CC	chloroplast stroma	The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.
GO:0009611	BP	response to wounding	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
GO:0009617	BP	response to bacterium	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
GO:0009723	BP	response to ethylene	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
GO:0009851	BP	auxin biosynthetic process	The chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
GO:0010311	BP	lateral root formation	The process that gives rise to a lateral root. This process pertains to the initial formation of a structure from unspecified parts. A lateral root primordium represents an organized group of cells derived from the root pericycle that will differentiate i
GO:0010600	BP	regulation of auxin biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of auxins, plant hormones that regulate aspects of plant growth.
GO:0046872	MF	metal ion binding	Interacting selectively and non-covalently with any metal ion.

Pubmed ID	Authors	Year	Title	Journal	Description
15579661	Celenza, J.L., Quiel, J.A., Smolen, G.A., Merrikh, H., Silvestro, A.R., Normanly, J. & Bender, J.	2005	The Arabidopsis ATR1 Myb Transcription Factor Controls Indolic Glucosinolate Homeostasis	Plant Physiology