SuCComBase

SCC Gene Description

Gene name	APR3
AGI ID	AT4G21990
Gene length	458
Uniprot ID	P92980
Protein Name	5'-adenylylsulfate reductase 3 chloroplastic
Synonym	PRH26
EC number	EC 1.8.4.9
Entrez Gene	828288
Refseq mrna	NM_118320
Refseq protein	NP_193930
Function	Using trans-activation assays two isoforms of APK; APK1 and APK2 are regulated by both classes of GSL MYB transcription factors; whereas two ATPS genes; ATPS1 and ATPS3 are differentially regulated by these two groups of MYB factors. The adenosine 5-phosphosulfate reductases APR1; APR2; and APR3 which participate in primary sulfate reduction are also activated by the MYB factors (Yatusevich et al. 2010)
Group	GSL core structure synthesis
Reference	Yatusevich et al. (2010)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value	Description
Broccoli	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	91	0.00E+00
Cabbage	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	89	0.00E+00
Cabbage	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	89	0.00E+00
Cabbage	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	88	0.00E+00
Broccoli	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	88	0.00E+00
Cabbage	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	82	0.00E+00
Broccoli	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	82	0.00E+00
Papaya	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	79	0.00E+00
Cabbage	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	76	0.00E+00
Papaya	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	76	0.00E+00
Papaya	AT4G21990	APR3	5'-adenylylsulfate reductase 3 chloroplastic	73	0.00E+00

GO ID	Ontology	GO Term	Description
GO:0000103	BP	sulfate assimilation	The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
GO:0004604	MF	phosphoadenylyl-sulfate reductase (thioredoxin) activity	Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known
GO:0009507	CC	chloroplast	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
GO:0009973	MF	adenylyl-sulfate reductase activity	Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.
GO:0016671	MF	oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor	Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.
GO:0019344	BP	cysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.
GO:0019419	BP	sulfate reduction	The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.
GO:0033741	MF	adenylyl-sulfate reductase (glutathione) activity	Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.
GO:0045454	BP	cell redox homeostasis	Any process that maintains the redox environment of a cell or compartment within a cell.
GO:0046872	MF	metal ion binding	Interacting selectively and non-covalently with any metal ion.
GO:0051539	MF	4 iron, 4 sulfur cluster binding	Interacting selectively and non-covalently with a 4 iron, 4 sulfur (4Fe-4S) cluster; this cluster consists of four iron atoms, with the inorganic sulfur atoms found between the irons and acting as bridging ligands.
GO:0055114	BP	oxidation-reduction process	A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

Pubmed ID	Authors	Year	Title	Journal	Description
20042022	Yatusevich, R., Mugford, S.G., Matthewman, C., Gigolashvili, T., Frerigmann, H., Delaney, S., Koprivova, A. & Flu, U.	2010	Genes of primary sulfate assimilation are part of the glucosinolate biosynthetic network in Arabidopsis thaliana	Plant Journal