Sulfur Containing Compound Database
Gene name | PEN2 |
AGI ID | AT2G44490 |
Gene length | 560 |
Uniprot ID | O64883 |
Protein Name | Beta-glucosidase 26 peroxisomal |
Synonym | BGLU26 |
EC number | EC 3.2.1.21 |
Entrez Gene | 819056 |
Refseq mrna | NM_130012 |
Refseq protein | NP_181977 |
Function | The Arabidopsis CYP81F2 gene encodes a P450 monooxygenase that is essential for the pathogen-induced accumulation of 4-methoxyindol-3-ylmethylGSL which in turn is activated by the atypical PEN2 myrosinase (a type of b-thioglucoside glucohydrolase) for antifungal defense (Bednarek et al. 2009) |
Group | GSL degradation / Camalexin biosynthesis |
Reference | Bednarek et al. (2009); Clay et al. (2009); Hiruma et al. (2010); Zhao et al. (2015); Cargnel et al. (2014) |
Organism | AGI ID | Gene Name | Protein Name | Identity | E-Value | Description |
---|---|---|---|---|---|---|
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
92 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
63 |
0.00E+00 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
62 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
62 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
61 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
61 |
0.00E+00 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
90 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
53 |
0.00E+00 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
54 |
0.00E+00 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
55 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
52 |
0.00E+00 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
53 |
0.00E+00 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
54 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
53 |
0.00E+00 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
53 |
0.00E+00 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
52 |
0.00E+00 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
53 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
52 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
52 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
52 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
52 |
0.00E+00 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
54 |
2.00E-178 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
52 |
6.00E-174 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
52 |
8.00E-172 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
47 |
2.00E-154 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
48 |
4.00E-154 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
45 |
1.00E-153 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
45 |
1.00E-152 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
46 |
2.00E-148 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
46 |
4.00E-147 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
46 |
6.00E-146 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
45 |
6.00E-146 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
44 |
8.00E-146 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
46 |
2.00E-144 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
46 |
5.00E-144 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
45 |
1.00E-142 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
45 |
2.00E-142 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
44 |
9.00E-142 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
44 |
1.00E-141 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
45 |
3.00E-141 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
45 |
6.00E-140 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
44 |
2.00E-137 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
43 |
4.00E-135 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
44 |
1.00E-133 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
43 |
7.00E-133 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
43 |
5.00E-132 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
43 |
7.00E-132 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
43 |
3.00E-131 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
43 |
7.00E-131 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
42 |
3.00E-130 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
42 |
6.00E-128 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
58 |
8.00E-126 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
41 |
5.00E-125 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
41 |
1.00E-123 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
41 |
4.00E-123 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
43 |
5.00E-123 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
40 |
7.00E-122 |
||
Cabbage |
PEN2 |
Beta-glucosidase 26 peroxisomal |
42 |
9.00E-121 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
41 |
1.00E-117 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
40 |
8.00E-117 |
||
Papaya |
PEN2 |
Beta-glucosidase 26 peroxisomal |
41 |
6.00E-116 |
||
Broccoli |
PEN2 |
Beta-glucosidase 26 peroxisomal |
40 |
3.00E-111 |
GO ID | Ontology | GO Term | Description |
---|---|---|---|
MF |
hydrolase activity, hydrolyzing O-glycosyl compounds |
Catalysis of the hydrolysis of any O-glycosyl bond. |
|
CC |
peroxisome |
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen |
|
BP |
carbohydrate metabolic process |
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule. |
|
MF |
beta-glucosidase activity |
Catalysis of the hydrolysis of terminal, non-reducing beta-D-glucose residues with release of beta-D-glucose. |
|
BP |
response to bacterium |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium. |
|
BP |
induced systemic resistance |
A response to non-pathogenic bacteria that confers broad spectrum systemic resistance to disease that does not depend upon salicylic acid signaling. |
|
BP |
defense response to fungus, incompatible interaction |
A response of an organism to a fungus that prevents the occurrence or spread of disease. |
|
CC |
chloroplast envelope |
The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space. |
|
CC |
membrane |
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it. |
|
MF |
thioglucosidase activity |
Catalysis of the reaction: a thioglucoside + H2O = a thiol + a sugar. |
|
BP |
glucosinolate metabolic process |
The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in anim |
|
BP |
indole glucosinolate catabolic process |
The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan. |
|
BP |
defense response to bacterium |
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. |
|
BP |
defense response by callose deposition in cell wall |
Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. |
|
MF |
scopolin beta-glucosidase activity |
Catalysis of the reaction: H2O + scopolin <=> beta-D-glucose + scopoletin |
Pubmed ID | Authors | Year | Title | Journal | Description |
---|---|---|---|---|---|
Bednarek, P., Pislewska-Bednarek, M., Svatos, A., Schneider, B., Doubsky, J., Mansurova, M., Humphry, M., Consonni, C., Panstruga, R., Sanchez-Vallet, A., Molina, A. & Schulze-Lefert, P. |
2009 |
A Glucosinolate Metabolism Pathway in Living Plant Cells Mediates Broad-Spectrum Antifungal Defense |
Science |
||
Clay, N.K., Adio, A.M., Denoux, C., Jander, G. & Ausubel, F.M. |
2009 |
Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response |
Science |
||
Hiruma, K., Onozawa-Komori, M., Takahashi, F., Asakura, M., Bednarek, P., Okuno, T., Schulze-Lefert, P. & Takano, Y. |
2010 |
Entry mode-dependent function of an indole glucosinolate pathway in Arabidopsis for nonhost resistance against anthracnose pathogens |
Plant Cell |
||
Zhao, Y., Wang, J., Liu, Y., Miao, H., Cai, C., Shao, Z., Guo, R., Sun, B., Jia, C., Zhang, L., Gigolashvili, T. & Wang, Q. |
2015 |
Classic myrosinase-dependent degradation of indole glucosinolate attenuates fumonisin B1-induced programmed cell death in Arabidopsis |
Plant Journal |