SuCComBase

SCC Gene Description

Gene name	PEN3
AGI ID	AT1G59870
Gene length	1469
Uniprot ID	Q9XIE2
Protein Name	ABC transporter G family member 36
Synonym	ABCG36
EC number	N/A
Entrez Gene	842281
Refseq mrna	NM_104680
Refseq protein	NP_176196
Function	Two genes; PEN2 and PEN3 are also necessary for resistance to pathogens and are required for both callose deposition and GSL activation suggesting that the pathogen-triggered callose response is required for resistance to microbial pathogens. The study shows that well- studied plant metabolites previously identified as important in avoiding damage by herbivores are also required as a component of the plant defense response against microbial pathogens (Clay et al. 2009)
Group	GSL degradation
Reference	Bednarek et al. (2009); Clay et al. (2009)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value
Papaya	AT1G59870	PEN3	ABC transporter G family member 36	74	0.00E+00
Papaya	AT1G59870	PEN3	ABC transporter G family member 36	58	0.00E+00
Papaya	AT1G59870	PEN3	ABC transporter G family member 36	58	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	58	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	58	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	57	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	56	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	55	0.00E+00
Papaya	AT1G59870	PEN3	ABC transporter G family member 36	56	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	55	0.00E+00
Papaya	AT1G59870	PEN3	ABC transporter G family member 36	55	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	52	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	52	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	50	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	50	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	48	0.00E+00
Papaya	AT1G59870	PEN3	ABC transporter G family member 36	57	0.00E+00
Papaya	AT1G59870	PEN3	ABC transporter G family member 36	56	0.00E+00
Papaya	AT1G59870	PEN3	ABC transporter G family member 36	55	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	50	0.00E+00
Papaya	AT1G59870	PEN3	ABC transporter G family member 36	55	0.00E+00
Broccoli	AT1G59870	PEN3	ABC transporter G family member 36	55	0.00E+00
Broccoli	AT1G59870	PEN3	ABC transporter G family member 36	49	0.00E+00
Broccoli	AT1G59870	PEN3	ABC transporter G family member 36	54	0.00E+00
Broccoli	AT1G59870	PEN3	ABC transporter G family member 36	42	0.00E+00
Broccoli	AT1G59870	PEN3	ABC transporter G family member 36	52	0.00E+00
Broccoli	AT1G59870	PEN3	ABC transporter G family member 36	50	0.00E+00
Broccoli	AT1G59870	PEN3	ABC transporter G family member 36	89	0.00E+00
Broccoli	AT1G59870	PEN3	ABC transporter G family member 36	84	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	84	0.00E+00
Cabbage	AT1G59870	PEN3	ABC transporter G family member 36	92	0.00E+00

GO ID	Ontology	GO Term	Description
GO:0005524	MF	ATP binding	Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0005739	CC	mitochondrion	A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
GO:0005774	CC	vacuolar membrane	The lipid bilayer surrounding the vacuole and separating its contents from the cytoplasm of the cell.
GO:0005886	CC	plasma membrane	The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
GO:0006855	BP	drug transmembrane transport	The process in which a drug is transported across a membrane.
GO:0009507	CC	chloroplast	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
GO:0009627	BP	systemic acquired resistance	The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.
GO:0009737	BP	response to abscisic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
GO:0009817	BP	defense response to fungus, incompatible interaction	A response of an organism to a fungus that prevents the occurrence or spread of disease.
GO:0009941	CC	chloroplast envelope	The double lipid bilayer enclosing the chloroplast and separating its contents from the rest of the cytoplasm; includes the intermembrane space.
GO:0015086	MF	cadmium ion transmembrane transporter activity	Enables the transfer of cadmium (Cd) ions from one side of a membrane to the other.
GO:0015691	BP	cadmium ion transport	The directed movement of cadmium (Cd) ions into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
GO:0016020	CC	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0016021	CC	integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0031348	BP	negative regulation of defense response	Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.
GO:0042344	BP	indole glucosinolate catabolic process	The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan.
GO:0042626	MF	ATPase activity, coupled to transmembrane movement of substances	Catalysis of the reaction: ATP + H2O = ADP + phosphate, to directly drive the active transport of a substance across a membrane.
GO:0042742	BP	defense response to bacterium	Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
GO:0052544	BP	defense response by callose deposition in cell wall	Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.
GO:0071366	BP	cellular response to indolebutyric acid stimulus	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an indolebutyric acid stimulus.

Pubmed ID	Authors	Year	Title	Journal	Description
19095900	Bednarek, P., Pislewska-Bednarek, M., Svatos, A., Schneider, B., Doubsky, J., Mansurova, M., Humphry, M., Consonni, C., Panstruga, R., Sanchez-Vallet, A., Molina, A. & Schulze-Lefert, P.	2009	A Glucosinolate Metabolism Pathway in Living Plant Cells Mediates Broad-Spectrum Antifungal Defense	Science
19095898	Clay, N.K., Adio, A.M., Denoux, C., Jander, G. & Ausubel, F.M.	2009	Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response	Science