SuCComBase

SCC Gene Description

Gene name	IGMT2
AGI ID	AT1G21120
Gene length	373
Uniprot ID	Q9LPU7
Protein Name	Indole glucosinolate O-methyltransferase 2
Synonym	T22I11.5
EC number	EC 2.1.1.-
Entrez Gene	838708
Refseq mrna	NM_101966
Refseq protein	NP_173536
Function	Arabidopsis O-methyl-transferase genes were found to coexpressed with CYP81F genes are fairly specific for the biosynthesis of modified indole GSLs which are IGMT1 and IGMT2. IGMT1 and 2 form a small gene cluster of O-MT genes on Arabidopsis chromosome 1 (Pfalz et al. 2011)
Group	GSL side chain modification
Reference	Pfalz et al. (2011)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	94	0.00E+00
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	93	0.00E+00
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	93	0.00E+00
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	93	0.00E+00
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	92	0.00E+00
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	90	0.00E+00
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	89	0.00E+00
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	73	0.00E+00
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	72	0.00E+00
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	74	0.00E+00
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	73	1.00E-178
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	78	8.00E-170
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	97	2.00E-142
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	56	5.00E-134
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	55	7.00E-125
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	55	8.00E-125
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	56	2.00E-124
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	53	3.00E-124
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	52	3.00E-124
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	56	2.00E-123
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	54	2.00E-122
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	53	2.00E-121
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	55	1.00E-118
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	51	3.00E-118
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	72	1.00E-117
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	53	9.00E-117
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	50	3.00E-115
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	51	5.00E-115
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	51	1.00E-105
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	52	2.00E-101
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	52	4.00E-101
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	47	4.00E-99
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	47	5.00E-98
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	46	4.00E-97
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	46	4.00E-97
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	46	8.00E-97
Papaya	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	47	2.00E-96
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	45	2.00E-96
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	53	2.00E-94
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	45	2.00E-93
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	45	9.00E-93
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	42	3.00E-90
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	63	3.00E-88
Cabbage	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	45	1.00E-86
Broccoli	AT1G21120	IGMT2	Indole glucosinolate O-methyltransferase 2	42	2.00E-70

GO ID	Ontology	GO Term	Description
GO:0005634	CC	nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some
GO:0005829	CC	cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0008168	MF	methyltransferase activity	Catalysis of the transfer of a methyl group to an acceptor molecule.
GO:0008171	MF	O-methyltransferase activity	Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.
GO:0008757	MF	S-adenosylmethionine-dependent methyltransferase activity	Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.
GO:0019438	BP	aromatic compound biosynthetic process	The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.
GO:0032259	BP	methylation	The process in which a methyl group is covalently attached to a molecule.
GO:0042343	BP	indole glucosinolate metabolic process	The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances b
GO:0046983	MF	protein dimerization activity	The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

Pubmed ID	Authors	Year	Title	Journal	Description
21317374	Pfalz, M., Mikkelsen, M.D., Olsen, C.E., Halkier, B.A. & Kroymann, J.	2011	Metabolic engineering in Nicotiana benthamiana reveals key enzyme functions in Arabidopsis indole glucosinolate modification	Plant Cell