Sulfur Containing Compound Database
| Gene name | PCS1 |
| AGI ID | AT5G44070 |
| Gene length | 485 |
| Uniprot ID | Q9S7Z3 |
| Protein Name | Glutathione gamma-glutamylcysteinyltransferase 1 |
| Synonym | CAD1 |
| EC number | EC 2.3.2.15 |
| Entrez Gene | 834430 |
| Refseq mrna | NM_123774 |
| Refseq protein | NP_199220 |
| Function | Microarray data of Flg22-inducible expression profiles identified a phytochelatin synthase gene; PCS1 whose corresponding mutants (pcs1-1; pcs1-2 and cad1-3) were all impaired in the callose response to Flg22. The transcriptional and indolic GSL profiles of the pcs1 mutant resemble those of the pen2 mutant; suggesting that it too is involved in the breakdown of 4-methoxy-indol-3-ylmethylGSL (Clay et al. 2009) |
| Group | GSL degradation / Camalexin biosynthesis |
| Reference | Clay et al. (2009); Su et al. (2011) |
| Organism | AGI ID | Gene Name | Protein Name | Identity | E-Value | Description |
|---|---|---|---|---|---|---|
Broccoli |
PCS1 |
Glutathione gamma-glutamylcysteinyltransferase 1 |
93 |
0.00E+00 |
||
Cabbage |
PCS1 |
Glutathione gamma-glutamylcysteinyltransferase 1 |
92 |
0.00E+00 |
||
Broccoli |
PCS1 |
Glutathione gamma-glutamylcysteinyltransferase 1 |
88 |
0.00E+00 |
||
Cabbage |
PCS1 |
Glutathione gamma-glutamylcysteinyltransferase 1 |
87 |
0.00E+00 |
||
Cabbage |
PCS1 |
Glutathione gamma-glutamylcysteinyltransferase 1 |
78 |
0.00E+00 |
||
Cabbage |
PCS1 |
Glutathione gamma-glutamylcysteinyltransferase 1 |
76 |
0.00E+00 |
||
Broccoli |
PCS1 |
Glutathione gamma-glutamylcysteinyltransferase 1 |
77 |
0.00E+00 |
||
Cabbage |
PCS1 |
Glutathione gamma-glutamylcysteinyltransferase 1 |
88 |
0.00E+00 |
||
Papaya |
PCS1 |
Glutathione gamma-glutamylcysteinyltransferase 1 |
67 |
0.00E+00 |
||
Papaya |
PCS1 |
Glutathione gamma-glutamylcysteinyltransferase 1 |
58 |
0.00E+00 |
| GO ID | Ontology | GO Term | Description |
|---|---|---|---|
MF |
copper ion binding |
Interacting selectively and non-covalently with copper (Cu) ions. |
|
CC |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
|
CC |
chloroplast |
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
|
MF |
ATPase-coupled arsenite transmembrane transporter activity |
Enables the transfer of a solute or solutes from one side of a membrane to the other according to the reaction: ATP + H2O + arsenite(in) = ADP + phosphate + arsenite(out). |
|
BP |
arsenite transport |
The directed movement of arsenite into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore. |
|
MF |
glutathione gamma-glutamylcysteinyltransferase activity |
Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly. |
|
BP |
indole glucosinolate catabolic process |
The chemical reactions and pathways resulting in the breakdown of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan. |
|
BP |
defense response to bacterium |
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism. |
|
BP |
response to arsenic-containing substance |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an arsenic stimulus from compounds containing arsenic, including arsenates, arsen |
|
BP |
response to cadmium ion |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus. |
|
MF |
cadmium ion binding |
Interacting selectively and non-covalently with cadmium (Cd) ions. |
|
BP |
phytochelatin biosynthetic process |
The chemical reactions and pathways resulting in the formation of phytochelatins, any of a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. The structure is of the type (gamma-glutamyl-cysteinyl)n-glycine, where |
|
BP |
defense response by callose deposition in cell wall |
Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls. |
|
MF |
phytochelatin transmembrane transporter activity |
Enables the directed movement of a phytochelatin from one side of a membrane to the other. Phytochelatins are a group of peptides that bind metals (Cd, Zn, Cu, Pb, Hg) in thiolate coordination complexes. |
| Pubmed ID | Authors | Year | Title | Journal | Description |
|---|---|---|---|---|---|
Clay, N.K., Adio, A.M., Denoux, C., Jander, G. & Ausubel, F.M. |
2009 |
Glucosinolate Metabolites Required for an Arabidopsis Innate Immune Response |
Science |