SuCComBase

SCC Gene Description

Gene name	CYP77A4
AGI ID	AT5G04660
Gene length	512
Uniprot ID	Q9LZ31
Protein Name	Cytochrome P450 77A4
Synonym	T1E3.20
EC number	EC 1.14.-.-
Entrez Gene	830343
Refseq mrna	NM_120548
Refseq protein	NP_196086
Function	Camalexin originates from tryptophan and its biosynthesis involves the cytochrome P450 enzymes CYP79B2 and CYP71B15 (PAD3). Camalexin induction is a complex process, for which triggering by reactive oxygen species (ROS), salicylic acid signalling, and the glutathione status are important. Targets of the signalling cascade are the tryptophan and camalexin biosynthetic genes, which are strongly transcriptionally upregulated at the sites of pathogen infection (Glawischnig et al. 2004) .
Group	Camalexin biosynthesis
Reference	Glawischnig et al. (2004)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value	Description
Papaya	AT5G04660	CYP77A4	Cytochrome P450 77A4	74.052	0
Papaya	AT5G04660	CYP77A4	Cytochrome P450 77A4	43.632	1.01E-123
Broccoli	AT5G04660	CYP77A4	Cytochrome P450 77A4	86.497	0
Broccoli	AT5G04660	CYP77A4	Cytochrome P450 77A4	80.507	0
Broccoli	AT5G04660	CYP77A4	Cytochrome P450 77A4	42.981	5.82E-129
Cabbage	AT5G04660	CYP77A4	Cytochrome P450 77A4	85.658	0
Cabbage	AT5G04660	CYP77A4	Cytochrome P450 77A4	79.532	0
Cabbage	AT5G04660	CYP77A4	Cytochrome P450 77A4	72.854	0
Cabbage	AT5G04660	CYP77A4	Cytochrome P450 77A4	42.981	8.08E-132
Cabbage	AT5G04660	CYP77A4	Cytochrome P450 77A4	43.197	5.93E-131
Cabbage	AT5G04660	CYP77A4	Cytochrome P450 77A4	40.179	3.66E-111

GO ID	Ontology	GO Term	Description
GO:0005506	MF	iron ion binding	Interacting selectively and non-covalently with iron (Fe) ions.
GO:0009507	CC	chloroplast	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
GO:0010143	BP	cutin biosynthetic process	The chemical reactions and pathways resulting in the formation of cutin, a waxy substance, which combined with cellulose forms a substance nearly impervious to water and constituting the cuticle in plants.
GO:0016020	CC	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0016021	CC	integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0016709	MF	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
GO:0019395	BP	fatty acid oxidation	The removal of one or more electrons from a fatty acid, with or without the concomitant removal of a proton or protons, by reaction with an electron-accepting substance, by addition of oxygen or by removal of hydrogen.
GO:0019825	MF	oxygen binding	Interacting selectively and non-covalently with oxygen (O2).
GO:0020037	MF	heme binding	Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
GO:0044550	BP	secondary metabolite biosynthetic process	The chemical reactions and pathways resulting in the formation of secondary metabolites, the compounds that are not necessarily required for growth and maintenance of cells, and are often unique to a taxon.
GO:0052722	MF	fatty acid in-chain hydroxylase activity	Catalysis of the reaction: fatty acid + O2 + 2 NADPH + H+ = fatty acid with in-chain hydroxy group + 2 NADP+ + H2O.

No references found.