SuCComBase

SCC Gene Description

Gene name	APK2
AGI ID	AT4G39940
Gene length	293
Uniprot ID	O49196
Protein Name	Adenylyl-sulfate kinase 2 chloroplastic
Synonym	AKN2
EC number	EC 2.7.1.25
Entrez Gene	830153
Refseq mrna	NM_120157
Refseq protein	NP_195704
Function	The levels of GSLs and the sulfated 12-hydroxyjasmonate were reduced approximately fivefold in apk1 apk2 plants. The reduction in GSLs resulted in increased transcript levels for genes involved in GSL biosynthesis and accumulation of desulfated precursors (Mugford et al. 2009)
Group	GSL core structure synthesis
Reference	Badenes-Perez et al. (2013); Mugford et al. (2009); Kopriva et al. (2009)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value	Description
Cabbage	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	90	0.00E+00
Cabbage	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	88	0.00E+00
Broccoli	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	88	0.00E+00
Broccoli	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	87	0.00E+00
Broccoli	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	87	0.00E+00
Broccoli	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	86	0.00E+00
Cabbage	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	84	3.00E-178
Papaya	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	68	3.00E-117
Papaya	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	59	9.00E-116
Broccoli	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	61	3.00E-112
Cabbage	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	61	3.00E-111
Cabbage	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	62	6.00E-108
Broccoli	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	73	7.00E-108
Cabbage	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	73	2.00E-107
Papaya	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	74	6.00E-99
Papaya	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	71	4.00E-91
Cabbage	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	62	3.00E-82
Broccoli	AT4G39940	APK2	Adenylyl-sulfate kinase 2 chloroplastic	52	3.00E-76

GO ID	Ontology	GO Term	Description
GO:0000103	BP	sulfate assimilation	The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.
GO:0004020	MF	adenylylsulfate kinase activity	Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.
GO:0005524	MF	ATP binding	Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.
GO:0009507	CC	chloroplast	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
GO:0009536	CC	plastid	Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.
GO:0010439	BP	regulation of glucosinolate biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
GO:0016301	MF	kinase activity	Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.
GO:0016310	BP	phosphorylation	The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.
GO:0016772	MF	transferase activity, transferring phosphorus-containing groups	Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).
GO:0019344	BP	cysteine biosynthetic process	The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.
GO:0048232	BP	male gamete generation	Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.
GO:0070814	BP	hydrogen sulfide biosynthetic process	The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

Pubmed ID	Authors	Year	Title	Journal	Description
23218016	Badenes-Perez, F.R., Reichelt, M., Gershenzon, J. & Heckel, D.G.	2013	Interaction of glucosinolate content of Arabidopsis thaliana mutant lines and feeding and oviposition by generalist and specialist lepidopterans	Phytochemistry
19304933	Mugford, S.G., Yoshimoto, N., Reichelt, M., Wirtz, M., Hill, L., Mugford, S.T., Noji, M., Takahashi, H., Kramell, R., Gigolashvili, T., Flu, U., Saito, K., Kopriva, S. & Gershenzon, J.	2009	Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites	Plant Cell
22833750	Kopriva, S., Mugford, S.G., Baraniecka, P., Lee, B.R., Matthewman, C.A. & Koprivova, A.	2012	Control of sulfur partitioning between primary and secondary metabolism in Arabidopsis	Front Plant Sci