SuCComBase

Sulfur Containing Compound Database

SCC Gene Description

Gene name GGT2
AGI ID AT4G39650
Gene length 552
Uniprot ID Q680I5
Protein Name Glutathione hydrolase 2
Synonym T19P19.40
EC number EC 3.4.19.13
Entrez Gene 830119
Refseq mrna NM_120125
Refseq protein NP_195675
Function GSTF6 overexpression increased and GSTF6-knockout reduced camalexin production. Arabidopsis GSTF6 expressed in yeast cells catalyzed GSH(IAN) formation. GSH(IAN), (IAN)CysGly, and γGluCys(IAN) were determined to be intermediates within the camalexin biosynthetic pathway. The expression of GSTF6, GGT1, GGT2, and PCS1 was coordinately upregulated during camalexin biosynthesis. These results suggest that GSH is the Cys derivative used during camalexin biosynthesis, that the conjugation of GSH with IAN is catalyzed by GSTF6, and that GGTs and PCS are involved in camalexin biosynthesis (Su et al. 2011).
Group Camalexin biosynthesis
Reference Su et al. (2011)
Organism AGI ID Gene Name Protein Name Identity E-Value Description

Papaya

AT4G39650

GGT2

Glutathione hydrolase 2

49.04

9.97E-168

Papaya

AT4G39650

GGT2

Glutathione hydrolase 2

50.814

7.27E-92

Papaya

AT4G39650

GGT2

Glutathione hydrolase 2

51.961

1.47E-60

Broccoli

AT4G39650

GGT2

Glutathione hydrolase 2

81.707

0

Broccoli

AT4G39650

GGT2

Glutathione hydrolase 2

81.533

0

Broccoli

AT4G39650

GGT2

Glutathione hydrolase 2

74.171

0

Broccoli

AT4G39650

GGT2

Glutathione hydrolase 2

49.387

7.35E-173

Broccoli

AT4G39650

GGT2

Glutathione hydrolase 2

47.669

2.18E-136

Broccoli

AT4G39650

GGT2

Glutathione hydrolase 2

50.15

4.58E-103

Broccoli

AT4G39650

GGT2

Glutathione hydrolase 2

43.493

9.65E-69

Broccoli

AT4G39650

GGT2

Glutathione hydrolase 2

73.643

6.35E-62

Broccoli

AT4G39650

GGT2

Glutathione hydrolase 2

41.256

1.02E-50

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

83.286

0

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

82.056

0

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

82.007

0

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

80.266

0

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

79.703

0

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

50.088

0

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

49.825

2.34E-174

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

76.433

1.15E-141

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

45.221

5.10E-140

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

42.823

3.47E-104

Cabbage

AT4G39650

GGT2

Glutathione hydrolase 2

78.626

1.86E-68

GO ID Ontology GO Term Description

GO:0005576

CC

extracellular region

A location, relative to cellular compartments and structures, occupied by a macromolecular machine when it carries out a molecular function. There are two ways in which the gene ontology describes locations of gene products: (1) relative to cellular struc

GO:0005886

CC

plasma membrane

The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.

GO:0006751

BP

glutathione catabolic process

The chemical reactions and pathways resulting in the breakdown of glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins.

GO:0016756

MF

glutathione gamma-glutamylcysteinyltransferase activity

Catalysis of the reaction: glutathione + Glu(-Cys)(n)-Gly = Gly + Glu(-Cys)(n+1)-Gly.

GO:0034775

BP

glutathione transmembrane transport

A process in which glutathione is transported across a membrane.

GO:0036374

MF

glutathione hydrolase activity

Catalysis of the reaction: glutathione + H2O = L-cysteinylglycine + L-glutamate.

GO:0048046

CC

apoplast

The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and

GO:0102953

MF

hypoglycin A gamma-glutamyl transpeptidase activity

Catalysis of the reaction: glutathionate + hypoglycin A = L-cysteinylglycine + hypoglycin B.

No references found.