SuCComBase

SCC Gene Description

Gene name	GGP1
AGI ID	AT4G30530
Gene length	250
Uniprot ID	Q9M0A7
Protein Name	Gamma-glutamyl peptidase 1
Synonym	AT4G30530
EC number	EC 3.4.19.-
Entrez Gene	829176
Refseq mrna	NM_119199
Refseq protein	NP_194782
Function	GGP1 is a gamma-glutamyl peptidase that cleaves off the gamma-glutamyl residue from the glutathione conjugate intermediate (S-[(Z)-phenylacetohydroximoyl]-L-glutathione; GS-B) in the benzylGSLs (BGLS) pathway (Geu-Flores et al. 2009)
Group	GSL core structure synthesis
Reference	Geu-Flores et al. (2009); Moldrup et al. (2011)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value	Description
Broccoli	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	89	1.00E-168
Cabbage	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	88	6.00E-166
Broccoli	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	88	1.00E-165
Cabbage	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	88	3.00E-164
Broccoli	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	88	1.00E-163
Cabbage	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	86	1.00E-158
Broccoli	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	73	4.00E-137
Cabbage	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	68	1.00E-127
Cabbage	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	67	7.00E-124
Cabbage	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	76	4.00E-122
Papaya	AT4G30530	GGP1	Gamma-glutamyl peptidase 1	45	2.00E-75

GO ID	Ontology	GO Term	Description
GO:0003824	MF	catalytic activity	Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific b
GO:0005737	CC	cytoplasm	All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0005829	CC	cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0006508	BP	proteolysis	The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds.
GO:0008233	MF	peptidase activity	Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid.
GO:0010120	BP	camalexin biosynthetic process	The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.
GO:0019760	BP	glucosinolate metabolic process	The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in anim
GO:0034722	MF	gamma-glutamyl-peptidase activity	Catalysis of the cleavage of a gamma-linked glutamate bond.

Pubmed ID	Authors	Year	Title	Journal	Description
19483696	Geu-Flores, F., Nielsen, M.T., Nafisi, M., M?ldrup, M.E., Olsen, C.E., Motawia, M.S. & Halkier, B.A.	2009	Glucosinolate engineering identifies a [gamma]-glutamyl peptidase	Nat Chem Biol
21281472	M?ldrup, M.E., Geu-flores, F., Olsen, C.E. & Halkier, B.A.	2011	Modulation of sulfur metabolism enables efficient glucosinolate engineering	BMC Biotechnol