Sulfur Containing Compound Database
| Gene name | GGP1 |
| AGI ID | AT4G30530 |
| Gene length | 250 |
| Uniprot ID | Q9M0A7 |
| Protein Name | Gamma-glutamyl peptidase 1 |
| Synonym | AT4G30530 |
| EC number | EC 3.4.19.- |
| Entrez Gene | 829176 |
| Refseq mrna | NM_119199 |
| Refseq protein | NP_194782 |
| Function | GGP1 is a gamma-glutamyl peptidase that cleaves off the gamma-glutamyl residue from the glutathione conjugate intermediate (S-[(Z)-phenylacetohydroximoyl]-L-glutathione; GS-B) in the benzylGSLs (BGLS) pathway (Geu-Flores et al. 2009) |
| Group | GSL core structure synthesis |
| Reference | Geu-Flores et al. (2009); Moldrup et al. (2011) |
| Organism | AGI ID | Gene Name | Protein Name | Identity | E-Value | Description |
|---|---|---|---|---|---|---|
|
Broccoli |
GGP1 |
Gamma-glutamyl peptidase 1 |
89 |
1.00E-168 |
||
|
Cabbage |
GGP1 |
Gamma-glutamyl peptidase 1 |
88 |
6.00E-166 |
||
|
Broccoli |
GGP1 |
Gamma-glutamyl peptidase 1 |
88 |
1.00E-165 |
||
|
Cabbage |
GGP1 |
Gamma-glutamyl peptidase 1 |
88 |
3.00E-164 |
||
|
Broccoli |
GGP1 |
Gamma-glutamyl peptidase 1 |
88 |
1.00E-163 |
||
|
Cabbage |
GGP1 |
Gamma-glutamyl peptidase 1 |
86 |
1.00E-158 |
||
|
Broccoli |
GGP1 |
Gamma-glutamyl peptidase 1 |
73 |
4.00E-137 |
||
|
Cabbage |
GGP1 |
Gamma-glutamyl peptidase 1 |
68 |
1.00E-127 |
||
|
Cabbage |
GGP1 |
Gamma-glutamyl peptidase 1 |
67 |
7.00E-124 |
||
|
Cabbage |
GGP1 |
Gamma-glutamyl peptidase 1 |
76 |
4.00E-122 |
||
|
Papaya |
GGP1 |
Gamma-glutamyl peptidase 1 |
45 |
2.00E-75 |
| GO ID | Ontology | GO Term | Description |
|---|---|---|---|
|
MF |
catalytic activity |
Catalysis of a biochemical reaction at physiological temperatures. In biologically catalyzed reactions, the reactants are known as substrates, and the catalysts are naturally occurring macromolecular substances known as enzymes. Enzymes possess specific b |
|
|
CC |
cytoplasm |
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures. |
|
|
CC |
cytosol |
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes. |
|
|
BP |
proteolysis |
The hydrolysis of proteins into smaller polypeptides and/or amino acids by cleavage of their peptide bonds. |
|
|
MF |
peptidase activity |
Catalysis of the hydrolysis of a peptide bond. A peptide bond is a covalent bond formed when the carbon atom from the carboxyl group of one amino acid shares electrons with the nitrogen atom from the amino group of a second amino acid. |
|
|
BP |
camalexin biosynthetic process |
The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin. |
|
|
BP |
glucosinolate metabolic process |
The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in anim |
|
|
MF |
gamma-glutamyl-peptidase activity |
Catalysis of the cleavage of a gamma-linked glutamate bond. |
| Pubmed ID | Authors | Year | Title | Journal | Description |
|---|---|---|---|---|---|
|
Geu-Flores, F., Nielsen, M.T., Nafisi, M., M?ldrup, M.E., Olsen, C.E., Motawia, M.S. & Halkier, B.A. |
2009 |
Glucosinolate engineering identifies a [gamma]-glutamyl peptidase |
Nat Chem Biol |
||
|
M?ldrup, M.E., Geu-flores, F., Olsen, C.E. & Halkier, B.A. |
2011 |
Modulation of sulfur metabolism enables efficient glucosinolate engineering |
BMC Biotechnol |