SuCComBase

SCC Gene Description

Gene name	CYP83A1
AGI ID	AT4G13770
Gene length	502
Uniprot ID	P48421
Protein Name	Cytochrome P450 83A1
Synonym	REF2
EC number	EC 1.14.-.-
Entrez Gene	827011
Refseq mrna	NM_117451
Refseq protein	NP_193113
Function	The GSL profiles of transgenic Arabidopsis overexpressing either CYP83A1 or CYP83B1 exhibited wild-type levels of indole GSLs (Naur et al. 2003)
Group	GSL core structure synthesis / Camalexin biosynthesis
Reference	Bak et al. (2001); Naur et al. (2003); Zang et al. (2009) ;Liu et al. (2016)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value	Description
Cabbage	AT4G13770	CYP83A1	Cytochrome P450 83A1	89	0.00E+00
Broccoli	AT4G13770	CYP83A1	Cytochrome P450 83A1	88	0.00E+00
Cabbage	AT4G13770	CYP83A1	Cytochrome P450 83A1	86	0.00E+00
Broccoli	AT4G13770	CYP83A1	Cytochrome P450 83A1	63	0.00E+00
Cabbage	AT4G13770	CYP83A1	Cytochrome P450 83A1	63	0.00E+00
Papaya	AT4G13770	CYP83A1	Cytochrome P450 83A1	59	0.00E+00
Papaya	AT4G13770	CYP83A1	Cytochrome P450 83A1	40	7.00E-115
Papaya	AT4G13770	CYP83A1	Cytochrome P450 83A1	40	8.00E-113
Papaya	AT4G13770	CYP83A1	Cytochrome P450 83A1	41	6.00E-112
Papaya	AT4G13770	CYP83A1	Cytochrome P450 83A1	41	3.00E-108

GO ID	Ontology	GO Term	Description
GO:0005506	MF	iron ion binding	Interacting selectively and non-covalently with iron (Fe) ions.
GO:0005789	CC	endoplasmic reticulum membrane	The lipid bilayer surrounding the endoplasmic reticulum.
GO:0009411	BP	response to UV	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ultraviolet radiation (UV light) stimulus. Ultraviolet radiation is electromag
GO:0009625	BP	response to insect	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.
GO:0016020	CC	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0016021	CC	integral component of membrane	The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
GO:0016709	MF	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.
GO:0019761	BP	glucosinolate biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
GO:0019825	MF	oxygen binding	Interacting selectively and non-covalently with oxygen (O2).
GO:0020037	MF	heme binding	Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.
GO:0055114	BP	oxidation-reduction process	A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

Pubmed ID	Authors	Year	Title	Journal	Description
11158532	Bak, S., Tax, F.E., Feldmann, K.A., Galbraith, D.W. & Feyereisen, R.	2001	CYP83B1, a Cytochrome P450 at the Metabolic Branch Point in Auxin and Indole Glucosinolate Biosynthesis in Arabidopsis	Plant Cell
12970475	Naur, P., Petersen, B.L., Mikkelsen, M.D., Bak, S., Rasmussen, H., Olsen, C.E. & Halkier, B.A.	2003	CYP83A1 and CYP83B1, Two Nonredundant Cytochrome P450 Enzymes Metabolizing Oximes in the Biosynthesis of Glucosinolates in Arabidopsis	Plant Physiology
N/A	Zang, Y.-X., Kim, D.-H., Park, B.-S. & Hong, S.-B.	2009	Metabolic engineering of indole glucosinolates in Chinese cabbage hairy roots expressing Arabidopsis CYP79B2, CYP79B3, and CYP83B1	Biotechnology and Bioprocess Engineering