SuCComBase

SCC Gene Description

Gene name	MYB118
AGI ID	AT3G27785
Gene length	437
Uniprot ID	Q9LVW4
Protein Name	Myb domain protein 118
Synonym	PGA37
EC number	N/A
Entrez Gene	822399
Refseq mrna	NM_113694
Refseq protein	NP_189416
Function	Two conserved TFs; MYB115 and MYB118 were co-expressed with the key enzyme encoding genes in the newly evolved benzoyloxy GSL (GLS) pathway. These TFs interacted with the promoters of the GLS biosynthetic genes and negatively influenced their expression. Similarly the GLS profiles of these two TFs knockouts showed that they influenced the aliphatic GLS accumulation within seed; leaf and flower while they mainly expressed in seeds (Zhang et al. 2015)
Group	GSL transcription factor
Reference	Zhang et al. (2015)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value
Cabbage	AT3G27785	MYB118	Myb domain protein 118	64	0.00E+00
Cabbage	AT3G27785	MYB118	Myb domain protein 118	61	0.00E+00
Broccoli	AT3G27785	MYB118	Myb domain protein 118	71	0.00E+00
Papaya	AT3G27785	MYB118	Myb domain protein 118	40	2.00E-59
Broccoli	AT3G27785	MYB118	Myb domain protein 118	57	4.00E-56
Broccoli	AT3G27785	MYB118	Myb domain protein 118	53	8.00E-55
Papaya	AT3G27785	MYB118	Myb domain protein 118	56	2.00E-53
Papaya	AT3G27785	MYB118	Myb domain protein 118	44	3.00E-53
Broccoli	AT3G27785	MYB118	Myb domain protein 118	72	3.00E-52
Broccoli	AT3G27785	MYB118	Myb domain protein 118	51	1.00E-51
Broccoli	AT3G27785	MYB118	Myb domain protein 118	59	4.00E-51

GO ID	Ontology	GO Term	Description
GO:0000981	MF	RNA polymerase II transcription factor activity, sequence-specific DNA binding	Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II.
GO:0001135	MF	transcription factor activity, RNA polymerase II transcription factor recruiting	Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II
GO:0003677	MF	DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0003700	MF	transcription factor activity, sequence-specific DNA binding	A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene in order to modulate transcription. Regulatory regions include promoter
GO:0005634	CC	nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some
GO:0006351	BP	transcription, DNA-templated	The cellular synthesis of RNA on a template of DNA.
GO:0006355	BP	regulation of transcription, DNA-templated	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0006357	BP	regulation of transcription from RNA polymerase II promoter	Any process that modulates the frequency, rate or extent of transcription mediated by RNA polymerase II.
GO:0009960	BP	endosperm development	The process whose specific outcome is the progression of the endosperm over time, from its formation to the mature structure. The endosperm is formed during fertilization and provides nutrients to the developing embryo.
GO:0010228	BP	vegetative to reproductive phase transition of meristem	The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.
GO:0010262	BP	somatic embryogenesis	Initiation of a somatic embryo-an embryo arising from previously differentiated somatic cells, rather than from fused haploid gametes.
GO:0010439	BP	regulation of glucosinolate biosynthetic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
GO:0030154	BP	cell differentiation	The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable pha
GO:0043565	MF	sequence-specific DNA binding	Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
GO:0044212	MF	transcription regulatory region DNA binding	Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a facto
GO:0045723	BP	positive regulation of fatty acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of fatty acids.
GO:0045893	BP	positive regulation of transcription, DNA-templated	Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
GO:0045995	BP	regulation of embryonic development	Any process that modulates the frequency, rate or extent of embryonic development.
GO:0055089	BP	fatty acid homeostasis	Any process involved in the maintenance of an internal steady state of fatty acid within an organism or cell.
GO:1904095	BP	negative regulation of endosperm development	Any process that stops, prevents or reduces the frequency, rate or extent of endosperm development.
GO:2000014	BP	regulation of endosperm development	Any process that modulates the frequency, rate or extent of endosperm development.
GO:2000034	BP	regulation of seed maturation	Any process that modulates the frequency, rate or extent of seed maturation.
GO:2000692	BP	negative regulation of seed maturation	Any process that stops, prevents or reduces the frequency, rate or extent of seed maturation.
GO:2001280	BP	positive regulation of unsaturated fatty acid biosynthetic process	Any process that activates or increases the frequency, rate or extent of unsaturated fatty acid biosynthetic process.

Pubmed ID	Authors	Year	Title	Journal	Description
26029237	Zhang, Y., Li, B., Huai, D., Zhou, Y. & Kliebenstein, D.J.	2015	The conserved transcription factors, MYB115 and MYB118, control expression of the newly evolved benzoyloxy glucosinolate pathway in Arabidopsis thaliana	Front Plant Sci