SuCComBase

SCC Gene Description

Gene name	GSTF11
AGI ID	AT3G03190
Gene length	214
Uniprot ID	Q96324
Protein Name	Glutathione S-transferase F11
Synonym	ATGSTF11
EC number	EC 2.5.1.18
Entrez Gene	821227
Refseq mrna	NM_111189
Refseq protein	NP_186969
Function	GST-type enzymes may be involved in an enzyme complex formed by CYP83s and C-S lyase. The S-alkylthiohydroximate formed after CYP83-catalyzed aldoxime oxidation and spontaneous conjugation to cysteine is cyclized in vitro to form a dead-end product. Hence metabolic channeling aided by GST-type enzymes is postulated in vivo to avoid this consequence the dead-end product. The two putative GST genes (At3g03190 and At1g78370) could be candidates coding for such an activity (Hirai et al. 2005)
Group	GSL core structure synthesis
Reference	Hirai et al. (2005); Hirai et al. (2007); Wentzell et al. (2007)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value	Description
Cabbage	AT3G03190	GSTF11	Glutathione S-transferase F11	80	3.00E-125
Broccoli	AT3G03190	GSTF11	Glutathione S-transferase F11	71	2.00E-114
Cabbage	AT3G03190	GSTF11	Glutathione S-transferase F11	70	1.00E-113
Broccoli	AT3G03190	GSTF11	Glutathione S-transferase F11	69	3.00E-112
Cabbage	AT3G03190	GSTF11	Glutathione S-transferase F11	70	8.00E-112
Papaya	AT3G03190	GSTF11	Glutathione S-transferase F11	61	2.00E-94
Papaya	AT3G03190	GSTF11	Glutathione S-transferase F11	49	4.00E-69
Cabbage	AT3G03190	GSTF11	Glutathione S-transferase F11	46	4.00E-63
Broccoli	AT3G03190	GSTF11	Glutathione S-transferase F11	46	9.00E-63
Broccoli	AT3G03190	GSTF11	Glutathione S-transferase F11	45	4.00E-62
Cabbage	AT3G03190	GSTF11	Glutathione S-transferase F11	45	5.00E-62
Papaya	AT3G03190	GSTF11	Glutathione S-transferase F11	45	2.00E-61
Broccoli	AT3G03190	GSTF11	Glutathione S-transferase F11	43	2.00E-60
Broccoli	AT3G03190	GSTF11	Glutathione S-transferase F11	47	4.00E-56
Broccoli	AT3G03190	GSTF11	Glutathione S-transferase F11	46	4.00E-55
Broccoli	AT3G03190	GSTF11	Glutathione S-transferase F11	45	2.00E-54
Broccoli	AT3G03190	GSTF11	Glutathione S-transferase F11	44	1.00E-51
Papaya	AT3G03190	GSTF11	Glutathione S-transferase F11	44	1.00E-51

GO ID	Ontology	GO Term	Description
GO:0004364	MF	glutathione transferase activity	Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
GO:0005737	CC	cytoplasm	All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0005829	CC	cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0006749	BP	glutathione metabolic process	The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific rol
GO:0006979	BP	response to oxidative stress	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactiv
GO:0009407	BP	toxin catabolic process	The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

Pubmed ID	Authors	Year	Title	Journal	Description
15866872	Hirai, M.Y., Klein, M., Fujikawa, Y., Yano, M., Goodenowe, D.B., Yamazaki, Y., Kanaya, S., Nakamura, Y., Kitayama, M., Suzuki, H., Sakurai, N., Shibata, D., Tokuhisa, J., Reichelt, M., Gershenzon, J., Papenbrock, J. & Saito, K.	2005	Elucidation of gene-to-gene and metabolite-to-gene networks in arabidopsis by integration of metabolomics and transcriptomics	J Biol Chem
17420480	Hirai, M.Y., Sugiyama, K., Sawada, Y., Tohge, T., Obayashi, T., Suzuki, A., Araki, R., Sakurai, N., Suzuki, H., Aoki, K., Goda, H. & Nishizawa, O.I.	2007	Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis	Proc Natl Acad Sci U S A
17941713	Wentzell, A.M., Rowe, H.C., Hansen, B.G., Ticconi, C., Halkier, B.A. & Kliebenstein, D.J.	2007	Linking metabolic QTLs with network and cis-eQTLs controlling biosynthetic pathways	PLoS Genet