SuCComBase

SCC Gene Description

Gene name	SUR1
AGI ID	AT2G20610
Gene length	462
Uniprot ID	Q9SIV0
Protein Name	S-alkyl-thiohydroximate lyase SUR1
Synonym	RTY1
EC number	EC 4.4.1.-
Entrez Gene	816585
Refseq mrna	NM_201760
Refseq protein	NP_973489
Function	SUPERROOT1 (SUR1) was characterized as the C-S lyase in GSL biosynthesis. This is supported by selective metabolite profiling of sur1 which is completely devoid of aliphatic and indolic GSLs (Mikkelsen et al. 2004)
Group	GSL core structure synthesis / Camalexin biosynthesis
Reference	Kong et al. (2015); Mikkelsen et al. (2004); Glawischnig et al. (2004)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	90	0.00E+00
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	86	0.00E+00
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	90	0.00E+00
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	72	0.00E+00
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	63	0.00E+00
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	62	0.00E+00
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	62	0.00E+00
Papaya	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	61	0.00E+00
Papaya	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	55	2.00E-175
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	60	2.00E-174
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	59	3.00E-173
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	58	7.00E-170
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	68	5.00E-165
Papaya	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	55	3.00E-155
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	52	3.00E-151
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	55	4.00E-151
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	48	3.00E-150
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	52	4.00E-150
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	48	4.00E-149
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	48	2.00E-146
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	59	6.00E-142
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	50	1.00E-136
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	51	2.00E-135
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	50	5.00E-132
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	48	1.00E-131
Cabbage	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	48	1.00E-123
Broccoli	AT2G20610	SUR1	S-alkyl-thiohydroximate lyase SUR1	50	2.00E-115

GO ID	Ontology	GO Term	Description
GO:0001560	BP	regulation of cell growth by extracellular stimulus	Any process in which external signals modulate the frequency, rate or extent of cell growth, the irreversible increase in size of a cell over time.
GO:0005737	CC	cytoplasm	All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0006520	BP	cellular amino acid metabolic process	The chemical reactions and pathways involving amino acids, carboxylic acids containing one or more amino groups, as carried out by individual cells.
GO:0008483	MF	transaminase activity	Catalysis of the transfer of an amino group to an acceptor, usually a 2-oxo acid.
GO:0009684	BP	indoleacetic acid biosynthetic process	The chemical reactions and pathways resulting in the formation of indole-3-acetic acid, a compound which functions as a growth regulator in plants.
GO:0016020	CC	membrane	A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
GO:0016846	MF	carbon-sulfur lyase activity	Catalysis of the elimination of hydrogen sulfide or substituted H2S.
GO:0019761	BP	glucosinolate biosynthetic process	The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
GO:0030170	MF	pyridoxal phosphate binding	Interacting selectively and non-covalently with pyridoxal 5' phosphate, 3-hydroxy-5-(hydroxymethyl)-2-methyl4-pyridine carboxaldehyde 5' phosphate, the biologically active form of vitamin B6.
GO:0048830	BP	adventitious root development	The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.
GO:0080108	MF	S-alkylthiohydroximate lyase activity	Catalysis of the conversion of a S-alkylthiohydroximate to a thiohydroximate.

Pubmed ID	Authors	Year	Title	Journal	Description
25552472	Kong, W., Li, Y., Zhang, M., Jin, F. & Li, J.	2015	A Novel Arabidopsis MicroRNA Promotes IAA Biosynthesis via the Indole-3-acetaldoxime Pathway by Suppressing SUPERROOT1	Plant and Cell Physiology
14871316	Mikkelsen, M.D., Naur, P. & Halkier, B.A.	2004	Arabidopsis mutants in the C?S lyase of glucosinolate biosynthesis establish a critical role for indole-3-acetaldoxime in auxin homeostasis	Plant Journal