SuCComBase

SCC Gene Description

Gene name	GSTU20
AGI ID	AT1G78370
Gene length	217
Uniprot ID	Q8L7C9
Protein Name	Glutathione S-transferase U20
Synonym	ATGSTU20
EC number	EC 2.5.1.18
Entrez Gene	844173
Refseq mrna	NM_106484
Refseq protein	NP_177958
Function	GST-type enzymes may be involved in an enzyme complex formed by CYP83s and C-S lyase. The S-alkylthiohydroximate formed after CYP83-catalyzed aldoxime oxidation and spontaneous conjugation to cysteine is cyclized in vitro to form a dead-end product. Hence metabolic channeling aided by GST-type enzymes is postulated in vivo to avoid this consequence the dead-end product. The two putative GST genes (At3g03190 and At1g78370) could be candidates coding for such an activity (Hirai et al. 2005)
Group	GSL core structure synthesis
Reference	Hirai et al. (2005); Hirai et al. (2007)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	89	3.00E-134
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	89	5.00E-134
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	73	3.00E-108
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	73	3.00E-108
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	69	6.00E-100
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	67	2.00E-99
Papaya	AT1G78370	GSTU20	Glutathione S-transferase U20	65	1.00E-98
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	66	1.00E-96
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	66	4.00E-96
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	64	5.00E-96
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	64	5.00E-95
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	60	3.00E-94
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	62	2.00E-93
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	62	3.00E-93
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	62	7.00E-93
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	64	1.00E-92
Papaya	AT1G78370	GSTU20	Glutathione S-transferase U20	61	2.00E-91
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	63	9.00E-90
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	63	2.00E-89
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	62	2.00E-89
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	59	3.00E-84
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	58	2.00E-80
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	58	1.00E-79
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	65	4.00E-78
Papaya	AT1G78370	GSTU20	Glutathione S-transferase U20	54	6.00E-78
Papaya	AT1G78370	GSTU20	Glutathione S-transferase U20	61	2.00E-77
Papaya	AT1G78370	GSTU20	Glutathione S-transferase U20	53	3.00E-77
Papaya	AT1G78370	GSTU20	Glutathione S-transferase U20	59	1.00E-76
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	57	7.00E-76
Papaya	AT1G78370	GSTU20	Glutathione S-transferase U20	59	2.00E-74
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	56	1.00E-72
Cabbage	AT1G78370	GSTU20	Glutathione S-transferase U20	53	2.00E-72
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	53	3.00E-72
Broccoli	AT1G78370	GSTU20	Glutathione S-transferase U20	51	8.00E-63
Papaya	AT1G78370	GSTU20	Glutathione S-transferase U20	49	9.00E-60
Papaya	AT1G78370	GSTU20	Glutathione S-transferase U20	57	1.00E-54

GO ID	Ontology	GO Term	Description
GO:0004364	MF	glutathione transferase activity	Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.
GO:0005634	CC	nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some
GO:0005737	CC	cytoplasm	All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0005829	CC	cytosol	The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
GO:0006749	BP	glutathione metabolic process	The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific rol
GO:0009407	BP	toxin catabolic process	The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.
GO:0009507	CC	chloroplast	A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.
GO:0009735	BP	response to cytokinin	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokinin stimulus.
GO:0019899	MF	enzyme binding	Interacting selectively and non-covalently with any enzyme.
GO:0040008	BP	regulation of growth	Any process that modulates the frequency, rate or extent of the growth of all or part of an organism so that it occurs at its proper speed, either globally or in a specific part of the organism's development.
GO:0048046	CC	apoplast	The cell membranes and intracellular regions in a plant are connected through plasmodesmata, and plants may be described as having two major compartments: the living symplast and the non-living apoplast. The apoplast is external to the plasma membrane and
GO:2000030	BP	regulation of response to red or far red light	Any process that modulates the frequency, rate or extent of response to red or far red light.

Pubmed ID	Authors	Year	Title	Journal	Description
15866872	Hirai, M.Y., Klein, M., Fujikawa, Y., Yano, M., Goodenowe, D.B., Yamazaki, Y., Kanaya, S., Nakamura, Y., Kitayama, M., Suzuki, H., Sakurai, N., Shibata, D., Tokuhisa, J., Reichelt, M., Gershenzon, J., Papenbrock, J. & Saito, K.	2005	Elucidation of gene-to-gene and metabolite-to-gene networks in arabidopsis by integration of metabolomics and transcriptomics	J Biol Chem
17420480	Hirai, M.Y., Sugiyama, K., Sawada, Y., Tohge, T., Obayashi, T., Suzuki, A., Araki, R., Sakurai, N., Suzuki, H., Aoki, K., Goda, H. & Nishizawa, O.I.	2007	Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis	Proc Natl Acad Sci U S A