SuCComBase

SCC Gene Description

Gene name	SLIM1
AGI ID	AT1G73730
Gene length	567
Uniprot ID	O23116
Protein Name	ETHYLENE INSENSITIVE 3-like 3 protein
Synonym	EIL3
EC number	N/A
Entrez Gene	843708
Refseq mrna	NM_106032
Refseq protein	NP_177514
Function	SLIM1 functioned as a central transcriptional regulator which controlled both the activation of sulfate acquisition and degradation of GSLs under –S conditions. Metabolite analysis indicated stable accumulation of GSLs in slim1 mutants; even under –S conditions; particularly in the molecular species with methylsulfinylalkyl side chains beneficial to human health (Maruyama-Nakashita et al. 2006)
Group	GSL transcription factor
Reference	Maruyama-Nakashita et al. (2006)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	84	0.00E+00
Broccoli	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	83	0.00E+00
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	82	0.00E+00
Broccoli	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	83	0.00E+00
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	79	0.00E+00
Papaya	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	62	1.00E-130
Broccoli	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	60	8.00E-129
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	60	9.00E-129
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	68	8.00E-128
Broccoli	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	61	2.00E-126
Papaya	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	53	2.00E-117
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	66	1.00E-116
Papaya	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	56	2.00E-97
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	52	1.00E-95
Broccoli	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	53	3.00E-94
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	55	4.00E-90
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	50	3.00E-89
Broccoli	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	47	2.00E-87
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	47	5.00E-87
Broccoli	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	47	2.00E-85
Cabbage	AT1G73730	SLIM1	ETHYLENE INSENSITIVE 3-like 3 protein	47	2.00E-85

GO ID	Ontology	GO Term	Description
GO:0003677	MF	DNA binding	Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
GO:0003700	MF	transcription factor activity, sequence-specific DNA binding	A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene in order to modulate transcription. Regulatory regions include promoter
GO:0005622	CC	intracellular	The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
GO:0005634	CC	nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some
GO:0006351	BP	transcription, DNA-templated	The cellular synthesis of RNA on a template of DNA.
GO:0006355	BP	regulation of transcription, DNA-templated	Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
GO:0009873	BP	ethylene-activated signaling pathway	A series of molecular signals generated by the reception of ethylene (ethene, C2H4) by a receptor and ending with modulation of a cellular process, e.g. transcription.
GO:0009970	BP	cellular response to sulfate starvation	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of sulfate.
GO:0042762	BP	regulation of sulfur metabolic process	Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving sulfur, the nonmetallic element sulfur or compounds that contain sulfur.
GO:0071281	BP	cellular response to iron ion	Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an iron ion stimulus.

Pubmed ID	Authors	Year	Title	Journal	Description
17114350	Maruyama-Nakashita, A., Nakamura, Y., Tohge, T., Saito, K. & Takahashi, H.	2006	Arabidopsis SLIM1 is a central transcriptional regulator of plant sulfur response and metabolism	Plant Cell