SuCComBase

SCC Gene Description

Gene name	ESP
AGI ID	AT1G54040
Gene length	341
Uniprot ID	Q8RY71
Protein Name	Epithiospecifier protein
Synonym	TASTY
EC number	N/A
Entrez Gene	841842
Refseq mrna	NM_180632
Refseq protein	NP_850963
Function	Myrosinase is not sufficient for indol-3-acetonitrile production from indol-3-ylmethyl GSL and requires the presence of functional epithospecifier protein (ESP) in planta and in vitro to produce significant levels of indol-3-acetonitrile (Burow et al. 2008)
Group	GSL degradation
Reference	Burow et al. (2008); Kuchernig et al. (2012)

Organism	AGI ID	Gene Name	Protein Name	Identity	E-Value
Cabbage	AT1G54040	ESP	Epithiospecifier protein	77	0.00E+00
Cabbage	AT1G54040	ESP	Epithiospecifier protein	77	0.00E+00
Broccoli	AT1G54040	ESP	Epithiospecifier protein	77	0.00E+00
Broccoli	AT1G54040	ESP	Epithiospecifier protein	77	0.00E+00
Broccoli	AT1G54040	ESP	Epithiospecifier protein	76	0.00E+00
Broccoli	AT1G54040	ESP	Epithiospecifier protein	76	0.00E+00
Broccoli	AT1G54040	ESP	Epithiospecifier protein	76	0.00E+00
Cabbage	AT1G54040	ESP	Epithiospecifier protein	76	0.00E+00
Cabbage	AT1G54040	ESP	Epithiospecifier protein	74	0.00E+00
Cabbage	AT1G54040	ESP	Epithiospecifier protein	58	1.00E-133
Cabbage	AT1G54040	ESP	Epithiospecifier protein	53	4.00E-121
Cabbage	AT1G54040	ESP	Epithiospecifier protein	57	3.00E-109
Cabbage	AT1G54040	ESP	Epithiospecifier protein	50	2.00E-108
Cabbage	AT1G54040	ESP	Epithiospecifier protein	49	1.00E-106
Cabbage	AT1G54040	ESP	Epithiospecifier protein	48	4.00E-102
Cabbage	AT1G54040	ESP	Epithiospecifier protein	57	2.00E-101
Cabbage	AT1G54040	ESP	Epithiospecifier protein	51	8.00E-97
Cabbage	AT1G54040	ESP	Epithiospecifier protein	48	3.00E-94
Papaya	AT1G54040	ESP	Epithiospecifier protein	45	2.00E-91
Broccoli	AT1G54040	ESP	Epithiospecifier protein	50	6.00E-75

GO ID	Ontology	GO Term	Description
GO:0005515	MF	protein binding	Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
GO:0005634	CC	nucleus	A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some
GO:0005737	CC	cytoplasm	All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
GO:0009753	BP	response to jasmonic acid	Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.
GO:0010150	BP	leaf senescence	The process that occurs in a leaf near the end of its active life that is associated with the dismantling of cell components and membranes, loss of functional chloroplasts, and an overall decline in metabolism.
GO:0019762	BP	glucosinolate catabolic process	The chemical reactions and pathways resulting in the breakdown of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.
GO:0030234	MF	enzyme regulator activity	Binds to and modulates the activity of an enzyme.
GO:0042742	BP	defense response to bacterium	Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

Pubmed ID	Authors	Year	Title	Journal	Description
17920088	Burow, M., Zhang, Z.Y., Ober, J.A., Lambrix, V.M., Wittstock, U., Gershenzon, J. & Kliebenstein, D.J.	2008	ESP and ESM1 mediate indol-3-acetonitrile production from indol-3-ylmethyl glucosinolate in Arabidopsis	Phytochemistry
22839361	Kuchernig, J.C., Burow, M. & Wittstock, U.	2012	Evolution of specifier proteins in glucosinolate-containing plants	BMC Evol Biol