Sulfur Containing Compound Database
Gene name | MYC2 |
AGI ID | AT1G32640 |
Gene length | 623 |
Uniprot ID | Q39204 |
Protein Name | Transcription factor MYC2 |
Synonym | AtbHLH6 |
EC number | N/A |
Entrez Gene | 840158 |
Refseq mrna | NM_102998.4 |
Refseq protein | NP_174541.1 |
Function | The myc2 myc3 myc4 (myc234) triple mutant was almost completely devoid of GSL and was extremely susceptible to the generalist herbivore Spodoptera littoralis. On the contrary the specialist Pieris brassicae was unaffected by the presence of GSL and preferred to feed on wild-type plants. In addition lack of GSL in myc234 drastically modified S. littoralis feeding behavior. Surprisingly the expression of MYB factors known to regulate GS biosynthesis genes was not altered in myc234; suggesting that MYC2/MYC3/MYC4 are necessary for direct transcriptional activation of GS biosynthesis genes. Yeast two-hybrid and pull-down experiments indicated that MYC2/MYC3/MYC4 interact directly with GS-related MYBs. This specific MYC–MYB interaction plays a crucial role in the regulation of defense secondary metabolite production and underlines the importance of GSL in shaping plant interactions with adapted and nonadapted herbivores (Schweizer et al. 2013) |
Group | GSL transcription factor |
Reference | Schweizer et al. (2013) |
Organism | AGI ID | Gene Name | Protein Name | Identity | E-Value | Description |
---|---|---|---|---|---|---|
Papaya |
MYC2 |
Transcription factor MYC2 |
59.248 |
0 |
||
Papaya |
MYC3 |
Transcription factor MYC3 |
52.792 |
1.26E-51 |
||
Broccoli |
MYC4 |
Transcription factor MYC4 |
84.727 |
0 |
||
Broccoli |
MYC5 |
Transcription factor MYC5 |
79.859 |
0 |
||
Broccoli |
MYC6 |
Transcription factor MYC6 |
52.484 |
4.43E-171 |
||
Broccoli |
MYC7 |
Transcription factor MYC7 |
48.029 |
5.17E-136 |
||
Broccoli |
MYC8 |
Transcription factor MYC8 |
47.133 |
7.64E-134 |
||
Broccoli |
MYC9 |
Transcription factor MYC9 |
49.251 |
1.50E-119 |
||
Broccoli |
MYC10 |
Transcription factor MYC10 |
64.929 |
1.61E-78 |
||
Broccoli |
MYC11 |
Transcription factor MYC11 |
59.358 |
1.37E-65 |
||
Broccoli |
MYC12 |
Transcription factor MYC12 |
55.721 |
5.61E-57 |
||
Cabbage |
MYC13 |
Transcription factor MYC13 |
85.323 |
0 |
||
Cabbage |
MYC14 |
Transcription factor MYC14 |
54.237 |
1.28E-166 |
||
Cabbage |
MYC15 |
Transcription factor MYC15 |
47.648 |
1.36E-159 |
||
Cabbage |
MYC16 |
Transcription factor MYC16 |
50.261 |
5.00E-146 |
||
Cabbage |
MYC17 |
Transcription factor MYC17 |
46.042 |
2.56E-139 |
||
Cabbage |
MYC18 |
Transcription factor MYC18 |
46.865 |
7.57E-61 |
||
Cabbage |
MYC19 |
Transcription factor MYC19 |
53.953 |
9.83E-61 |
||
Cabbage |
MYC20 |
Transcription factor MYC20 |
48 |
4.89E-56 |
GO ID | Ontology | GO Term | Description |
---|---|---|---|
MF |
DNA binding |
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid). |
|
MF |
transcription factor activity, sequence-specific DNA binding |
A protein or a member of a complex that interacts selectively and non-covalently with a specific DNA sequence (sometimes referred to as a motif) within the regulatory region of a gene in order to modulate transcription. Regulatory regions include promoter |
|
MF |
protein binding |
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules). |
|
CC |
nucleus |
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some |
|
BP |
transcription, DNA-templated |
The cellular synthesis of RNA on a template of DNA. |
|
BP |
tryptophan metabolic process |
The chemical reactions and pathways involving tryptophan, the chiral amino acid 2-amino-3-(1H-indol-3-yl)propanoic acid. |
|
BP |
response to desiccation |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a desiccation stimulus, extreme dryness resulting from the prolonged deprivation |
|
BP |
response to wounding |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism. |
|
BP |
response to abscisic acid |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus. |
|
BP |
abscisic acid-activated signaling pathway |
A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription. |
|
BP |
response to jasmonic acid |
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus. |
|
BP |
indole glucosinolate biosynthetic process |
The chemical reactions and pathways resulting in the formation of indole glucosinolates, sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan. |
|
BP |
jasmonic acid mediated signaling pathway |
A series of molecular signals mediated by jasmonic acid. |
|
BP |
positive regulation of flavonoid biosynthetic process |
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of flavonoids. |
|
BP |
response to chitin |
A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus. |
|
MF |
sequence-specific DNA binding |
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding. |
|
BP |
regulation of transcription from RNA polymerase II promoter in response to oxidative stress |
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e |
|
BP |
positive regulation of transcription, DNA-templated |
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription. |
|
MF |
protein dimerization activity |
The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits. |
|
BP |
root development |
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwar |
|
BP |
regulation of sequence-specific DNA binding transcription factor activity |
Any process that modulates the frequency, rate or extent of the activity of a transcription factor, any factor involved in the initiation or regulation of transcription. |
|
BP |
regulation of defense response to insect |
Any process that modulates the frequency, rate or extent of defense response to insect. |
Pubmed ID | Authors | Year | Title | Journal | Description |
---|---|---|---|---|---|
Schweizer, F., Fern?ndez-calvo, P., Zander, M., Diez-diaz, M., Fonseca, S., Glauser, G., Lewsey, M.G., Ecker, J.R., Solano, R. & Reymond, P. |
2013 |
Arabidopsis Basic Helix-Loop-Helix Transcription Factors MYC2,MYC3, andMYC4RegulateGlucosinolate Biosynthesis, Insect Performance, and Feeding Behavior |
The Plant Cell |