SuCComBase

Sulfur Containing Compound Database

SCC Gene Description

Gene name UGT74B1
AGI ID AT1G24100
Gene length 460
Uniprot ID O48676
Protein Name UDP-glycosyltransferase 74B1
Synonym N/A
EC number EC 2.4.1.- EC 2.4.1.195
Entrez Gene 839022
Refseq mrna NM_102256
Refseq protein NP_173820
Function Analysis of UGT74B1 promoter activity during plant development reveals expression patterns consistent with GSL metabolism and induction by auxin treatment. The results are discussed in the context of known mutations in GSL pathway genes and their effects on auxin homeostasis. This research provides complementary in vitro and in vivo evidence for a primary role of UGT74B1 in GSL biosynthesis (Grubb et al. 2004)
Group GSL core structure synthesis
Reference Grubb et al. (2004)
Organism AGI ID Gene Name Protein Name Identity E-Value Description

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

85

0.00E+00

Broccoli

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

86

0.00E+00

Papaya

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

57

6.00E-178

Papaya

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

53

4.00E-160

Papaya

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

44

9.00E-121

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

45

2.00E-119

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

44

7.00E-118

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

44

1.00E-117

Papaya

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

44

5.00E-117

Broccoli

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

43

2.00E-116

Broccoli

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

44

9.00E-116

Broccoli

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

42

3.00E-114

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

41

8.00E-114

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

43

1.00E-113

Broccoli

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

43

3.00E-113

Broccoli

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

42

5.00E-111

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

42

2.00E-107

Broccoli

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

40

3.00E-106

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

40

5.00E-105

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

40

8.00E-104

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

42

5.00E-103

Papaya

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

47

5.00E-103

Broccoli

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

41

1.00E-102

Broccoli

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

40

1.00E-102

Cabbage

AT1G24100

UGT74B1

UDP-glycosyltransferase 74B1

41

2.00E-100

GO ID Ontology GO Term Description

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0008194

MF

UDP-glycosyltransferase activity

Catalysis of the transfer of a glycosyl group from a UDP-sugar to a small hydrophobic molecule.

GO:0016757

MF

transferase activity, transferring glycosyl groups

Catalysis of the transfer of a glycosyl group from one compound (donor) to another (acceptor).

GO:0019761

BP

glucosinolate biosynthetic process

The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0042742

BP

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

GO:0043231

CC

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

GO:0047251

MF

thiohydroximate beta-D-glucosyltransferase activity

Catalysis of the reaction: phenylthioacetohydroximate + UDP-D-glucose = desulfoglucotropeolin + UDP.

GO:0052544

BP

defense response by callose deposition in cell wall

Any process in which callose is transported to, and/or maintained in, the cell wall during the defense response. Callose is a linear 1,3-beta-d-glucan formed from UDP-glucose and is found in certain plant cell walls.

GO:0080043

MF

quercetin 3-O-glucosyltransferase activity

Catalysis of the transfer of a glucosyl group from UDP-glucose to the 3-hydroxy group of a quercetin molecule.

GO:0080044

MF

quercetin 7-O-glucosyltransferase activity

Catalysis of the transfer of a glucosyl group from UDP-glucose to the 7-hydroxy group of a quercetin molecule.

GO:0102659

MF

UDP-glucose: 4-methylthiobutylhydroximate S-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + 4-methylthiobutylhydroximate <=> H+ + 3-methylthiopropyl-desulfoglucosinolate + UDP

GO:0103099

MF

UDP-glucose:5-methylthiopentylhydroximate S-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + 5-methylthiopentylhydroximate <=> H+ + 4-methylthiobutyldesulfoglucosinolate + UDP.

GO:0103100

MF

UDP-glucose: 6-methylthiohexylhydroximate S-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + 6-methylthiohexylhydroximate <=> H+ + 5-methylthiopentyldesulfoglucosinolate + UDP(3-).

GO:0103101

MF

UDP-glucose:7-methylthioheptylhydroximate S-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + 7-methylthioheptylhydroximate <=> H+ + 6-methylthiohexyldesulfoglucosinolate + UDP

GO:0103102

MF

UDP-glucose:8-methylthiooctylhydroximate S-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + 8-methylthiooctylhydroximate <=> H+ + 7-methylthioheptyldesulfoglucosinolate + UDP

GO:0103103

MF

UDP-glucose: 9-methylthiononylhydroximate S-glucosyltransferase activity

Catalysis of the reaction: UDP-alpha-D-glucose + 9-methylthiononylhydroximate <=> 8-methylthiooctyldesulfoglucosinolate + UDP + H+

Pubmed ID Authors Year Title Journal Description

15584955

Grubb, C.D., Zipp, B.J., Ludwig-Muller, J., Masuno, M.N., Molinski, T.F. & Abel, S.

2004

Arabidopsis glucosyltransferase UGT74B1 functions in glucosinolate biosynthesis and auxin homeostasis

Plant Journal