SuCComBase

Sulfur Containing Compound Database

SCC Gene Description

Gene name FMOGS-OX6
AGI ID AT1G12130
Gene length 470
Uniprot ID Q9FWW3
Protein Name Flavin-containing monooxygenase FMO GS-OX6
Synonym T28K15.13
EC number N/A
Entrez Gene 837765
Refseq mrna NM_101085
Refseq protein NP_172677
Function Two additional FMOGS-OX enzymes; FMOGS-OX6 and FMOGS-OX7 encoded by At1g12130 and At1g12160 respectively. The overexpression of both FMOGS-OX6 and FMOGS-OX7 decreased the ratio of methylthioalkyl GSLs to the sum of methylthioalkyl and methylsulfinylalkyl GSLs suggesting that the introduction of the two genes converted methylthioalkyl GSLs into methylsulfinylalkyl GSLs (Kong et al. 2016)
Group GSL side chain modificatian
Reference Kong et al. (2016 )
Organism AGI ID Gene Name Protein Name Identity E-Value Description

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

62

0.00E+00

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

64

0.00E+00

Broccoli

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

61

0.00E+00

Broccoli

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

61

0.00E+00

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

62

0.00E+00

Broccoli

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

63

0.00E+00

Broccoli

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

62

0.00E+00

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

62

0.00E+00

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

59

2.00E-178

Papaya

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

62

1.00E-177

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

60

4.00E-170

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

59

5.00E-169

Broccoli

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

49

2.00E-116

Broccoli

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

49

4.00E-116

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

48

4.00E-115

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

48

2.00E-111

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

44

4.00E-110

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

47

3.00E-103

Cabbage

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

50

9.00E-98

Broccoli

AT1G12130

FMOGS-OX6

Flavin-containing monooxygenase FMO GS-OX6

44

8.00E-96

GO ID Ontology GO Term Description

GO:0004497

MF

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

GO:0004499

MF

N,N-dimethylaniline monooxygenase activity

Catalysis of the reaction: N,N-dimethylaniline + NADPH + H+ + O2 = N,N-dimethylaniline N-oxide + NADP+ + H2O.

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0009737

BP

response to abscisic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.

GO:0009751

BP

response to salicylic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a salicylic acid stimulus.

GO:0009753

BP

response to jasmonic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a jasmonic acid stimulus.

GO:0019761

BP

glucosinolate biosynthetic process

The chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0050660

MF

flavin adenine dinucleotide binding

Interacting selectively and non-covalently with FAD, flavin-adenine dinucleotide, the coenzyme or the prosthetic group of various flavoprotein oxidoreductase enzymes, in either the oxidized form, FAD, or the reduced form, FADH2.

GO:0050661

MF

NADP binding

Interacting selectively and non-covalently with nicotinamide-adenine dinucleotide phosphate, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NADP+, or the reduced form, NADPH.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

Pubmed ID Authors Year Title Journal Description

27621741

Kong, W., Li, J., Yu, Q., Cang, W., Xu, R., Wang, Y. & Ji, W.

2016

Two Novel Flavin-Containing Monooxygenases Involved in Biosynthesis of Aliphatic Glucosinolates

Front Plant Sci