Sulfur Containing Compound Database

Arabidopsis Compound Description

Knapsack ID C00000125
PubChem ID 656506
Compound name 3-Indolylmethylglucosinolate (I3M)
Common Name Glucobrassicin
Formula C16H20N2O9S2
SCC Type Tryptophan derived glucosinolates; Indolylmethyl glucosinolates
SCC Function The metabolic products of glucobrassicin, indole-3-carbinol inhibit prostate cancer by both blocking initiation and suppressing prostate cancer progression in vitro and in vivo. With regards to suppressive activity, indole-3-carbinol has the ability to antagonize cell signaling pathways known to be dysregulated in prostate cancer (Watson et al. 2013).
Chemical Structure Responsive image
Pubmed ID Authors Year Title Journal Description


Kliebenstein, D. J., Kroymann, J., Brown, P., Figuth, A., Pedersen, D., Gershenzon, J. & Mitchell-Olds, T.


Genetic Control of Natural Variation in Arabidopsis Glucosinolate Accumulation

Plant Physiology


Brown, P.D., Tokuhisa, J.G., Reichelt, M. & Gershenzon, J.


Variation of glucosinolate accumulation among different organs and developmental stages of Arabidopsis thaliana



Watson, G. W., Beaver, L. M., Williams, D. E., Dashwood, R. H., & Ho, E.


Phytochemicals from cruciferous vegetables, epigenetics, and prostate cancer prevention.

The AAPS journal