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GO:0004559
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MF
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alpha-mannosidase activity
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Catalysis of the hydrolysis of terminal, non-reducing alpha-D-mannose residues in alpha-D-mannosides.
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|
GO:0004571
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MF
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mannosyl-oligosaccharide 1,2-alpha-mannosidase activity
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Catalysis of the hydrolysis of the terminal (1->2)-linked alpha-D-mannose residues in an oligo-mannose oligosaccharide.
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|
GO:0005509
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MF
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calcium ion binding
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Interacting selectively and non-covalently with calcium ions (Ca2+).
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|
GO:0005783
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CC
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endoplasmic reticulum
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The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisterna
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GO:0005789
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CC
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endoplasmic reticulum membrane
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The lipid bilayer surrounding the endoplasmic reticulum.
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|
GO:0005794
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CC
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Golgi apparatus
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A compound membranous cytoplasmic organelle of eukaryotic cells, consisting of flattened, ribosome-free vesicles arranged in a more or less regular stack. The Golgi apparatus differs from the endoplasmic reticulum in often having slightly thicker membrane
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|
GO:0006486
|
BP
|
protein glycosylation
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A protein modification process that results in the addition of a carbohydrate or carbohydrate derivative unit to a protein amino acid, e.g. the addition of glycan chains to proteins.
|
|
GO:0006487
|
BP
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protein N-linked glycosylation
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A protein glycosylation process in which a carbohydrate or carbohydrate derivative unit is added to a protein via the N4 atom of peptidyl-asparagine, the omega-N of arginine, or the N1' atom peptidyl-tryptophan.
|
|
GO:0006491
|
BP
|
N-glycan processing
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The conversion of N-linked glycan (N = nitrogen) structures from the initially transferred oligosaccharide to a mature form, by the actions of glycosidases and glycosyltransferases. The early processing steps are conserved and play roles in glycoprotein f
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|
GO:0008152
|
BP
|
metabolic process
|
The chemical reactions and pathways, including anabolism and catabolism, by which living organisms transform chemical substances. Metabolic processes typically transform small molecules, but also include macromolecular processes such as DNA repair and rep
|
|
GO:0016020
|
CC
|
membrane
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A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
|
GO:0016021
|
CC
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integral component of membrane
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The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
|
GO:0030433
|
BP
|
ubiquitin-dependent ERAD pathway
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The series of steps necessary to target endoplasmic reticulum (ER)-resident proteins for degradation by the cytoplasmic proteasome. Begins with recognition of the ER-resident protein, includes retrotranslocation (dislocation) of the protein from the ER to
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