Sulfur Containing Compound Database
Gene name | IDH-V |
AGI ID | AT5G03290 |
Gene length | 374 |
Uniprot ID | Q945K7 |
Protein Name | Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial |
Synonym | F12E4_20 |
EC number | 1.1.1.41 |
Entrez Gene | 831884 |
Refseq mrna | NM_120407 |
Refseq protein | NP_568113 |
Database |
GeneMANIA GeneMANIA GeneMANIA GeneMANIA GeneMANIA GeneMANIA GeneMANIA GeneMANIA |
GO ID | Ontology | GO Term | Description |
---|---|---|---|
MF |
magnesium ion binding |
Interacting selectively and non-covalently with magnesium (Mg) ions. |
|
MF |
isocitrate dehydrogenase (NAD+) activity |
Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+ |
|
MF |
ATP binding |
Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator. |
|
CC |
mitochondrion |
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration. |
|
BP |
tricarboxylic acid cycle |
A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes s |
|
BP |
isocitrate metabolic process |
The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle. |
|
MF |
zinc ion binding |
Interacting selectively and non-covalently with zinc (Zn) ions. |
|
CC |
chloroplast |
A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma. |
|
MF |
NAD binding |
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH. |