SuCComBase

Sulfur Containing Compound Database

Potential SCC Gene Description

Gene name IDH-V
AGI ID AT5G03290
Gene length 374
Uniprot ID Q945K7
Protein Name Isocitrate dehydrogenase [NAD] catalytic subunit 5, mitochondrial
Synonym F12E4_20
EC number 1.1.1.41
Entrez Gene 831884
Refseq mrna NM_120407
Refseq protein NP_568113
Database GeneMANIA
GeneMANIA
GeneMANIA
GeneMANIA
GeneMANIA
GeneMANIA
GeneMANIA
GeneMANIA
GO ID Ontology GO Term Description

GO:0000287

MF

magnesium ion binding

Interacting selectively and non-covalently with magnesium (Mg) ions.

GO:0004449

MF

isocitrate dehydrogenase (NAD+) activity

Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO:0005739

CC

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

GO:0006099

BP

tricarboxylic acid cycle

A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes s

GO:0006102

BP

isocitrate metabolic process

The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.

GO:0008270

MF

zinc ion binding

Interacting selectively and non-covalently with zinc (Zn) ions.

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0051287

MF

NAD binding

Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.