SuCComBase

Sulfur Containing Compound Database

Potential SCC Gene Description

Gene nameIDH1
AGI IDAT4G35260
Gene length367
Uniprot IDQ8LFC0
Protein NameIsocitrate dehydrogenase [NAD] regulatory subunit 1, mitochondrial
SynonymF23E12.180
EC numberN/A
Entrez Gene829679
Refseq mrnaNM_119692.3
Refseq proteinNP_195252.1
Database
GO IDOntologyGO TermDescription

GO:0004449

MF

isocitrate dehydrogenase (NAD+) activity

Catalysis of the reaction: isocitrate + NAD+ = 2-oxoglutarate + CO2 + NADH + H+

GO:0005739

CC

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

GO:0006099

BP

tricarboxylic acid cycle

A nearly universal metabolic pathway in which the acetyl group of acetyl coenzyme A is effectively oxidized to two CO2 and four pairs of electrons are transferred to coenzymes. The acetyl group combines with oxaloacetate to form citrate, which undergoes s

GO:0006102

BP

isocitrate metabolic process

The chemical reactions and pathways involving isocitrate, the anion of isocitric acid, 1-hydroxy-1,2,3-propanetricarboxylic acid. Isocitrate is an important intermediate in the TCA cycle and the glycoxylate cycle.

GO:0008270

MF

zinc ion binding

Interacting selectively and non-covalently with zinc (Zn) ions.