SuCComBase

GO:0000184

BP

nuclear-transcribed mRNA catabolic process, nonsense-mediated decay

The nonsense-mediated decay pathway for nuclear-transcribed mRNAs degrades mRNAs in which an amino-acid codon has changed to a nonsense codon; this prevents the translation of such mRNAs into truncated, and potentially harmful, proteins.

GO:0003723

MF

RNA binding

Interacting selectively and non-covalently with an RNA molecule or a portion thereof.

GO:0003725

MF

double-stranded RNA binding

Interacting selectively and non-covalently with double-stranded RNA.

GO:0004647

MF

phosphoserine phosphatase activity

Catalysis of the reaction: L(or D)-O-phosphoserine + H2O = L(or D)-serine + phosphate.

GO:0004721

MF

phosphoprotein phosphatase activity

Catalysis of the reaction: a phosphoprotein + H2O = a protein + phosphate. Together with protein kinases, these enzymes control the state of phosphorylation of cell proteins and thereby provide an important mechanism for regulating cellular activity.

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0006351

BP

transcription, DNA-templated

The cellular synthesis of RNA on a template of DNA.

GO:0007275

BP

multicellular organism development

The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).

GO:0008420

MF

CTD phosphatase activity

Catalysis of the reaction: phospho-(DNA-directed RNA polymerase) + H2O = (DNA-directed RNA polymerase) + phosphate.

GO:0009611

BP

response to wounding

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.

GO:0009651

BP

response to salt stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (parti

GO:0009738

BP

abscisic acid-activated signaling pathway

A series of molecular signals generated by the binding of the plant hormone abscisic acid (ABA) to a receptor, and ending with modulation of a cellular process, e.g. transcription.

GO:0016591

CC

DNA-directed RNA polymerase II, holoenzyme

A nuclear DNA-directed RNA polymerase complex containing an RNA polymerase II core enzyme as well as additional proteins and transcription factor complexes, that are capable of promoter recognition and transcription initiation from an RNA polymerase II pr

GO:0016607

CC

nuclear speck

A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.

GO:0016791

MF

phosphatase activity

Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.

GO:0045892

BP

negative regulation of transcription, DNA-templated

Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.

GO:0046872

MF

metal ion binding

Interacting selectively and non-covalently with any metal ion.

GO:0070940

BP

dephosphorylation of RNA polymerase II C-terminal domain

The process of removing a phosphate group from an amino acid residue in the C-terminal domain of RNA polymerase II. Some dephosphorylation occurs during transcription while some may occur after the enzyme is released from the template in order to prepare