SuCComBase

Sulfur Containing Compound Database

Potential SCC Gene Description

Gene name NAD-ME1
AGI ID AT2G13560
Gene length 623
Uniprot ID Q9SIU0
Protein Name NAD-dependent malic enzyme 1, mitochondrial
Synonym T10F5.10
EC number N/A
Entrez Gene 815842
Refseq mrna NM_126936.4
Refseq protein NP_178980.1
Database
GO ID Ontology GO Term Description

GO:0004470

MF

malic enzyme activity

Catalysis of the oxidative decarboxylation of malate with the concomitant production of pyruvate.

GO:0004471

MF

malate dehydrogenase (decarboxylating) (NAD+) activity

Catalysis of the reaction: (S)-malate + NAD+ = pyruvate + CO2 + NADH + H+.

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO:0005739

CC

mitochondrion

A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.

GO:0006090

BP

pyruvate metabolic process

The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.

GO:0006108

BP

malate metabolic process

The chemical reactions and pathways involving malate, the anion of hydroxybutanedioic acid, a chiral hydroxydicarboxylic acid. The (+) enantiomer is an important intermediate in metabolism as a component of both the TCA cycle and the glyoxylate cycle.

GO:0008270

MF

zinc ion binding

Interacting selectively and non-covalently with zinc (Zn) ions.

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009651

BP

response to salt stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of salt (parti

GO:0016652

MF

oxidoreductase activity, acting on NAD(P)H, NAD(P) as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which NADH or NADPH acts as a hydrogen or electron donor and reduces NAD+ or NADP.

GO:0042803

MF

protein homodimerization activity

Interacting selectively and non-covalently with an identical protein to form a homodimer.

GO:0050897

MF

cobalt ion binding

Interacting selectively and non-covalently with a cobalt (Co) ion.

GO:0051287

MF

NAD binding

Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.