SuCComBase

Sulfur Containing Compound Database

SCC Gene Description

Gene name CYP71B15
AGI ID AT3G26830
Gene length 490
Uniprot ID Q9LW27
Protein Name Bifunctional dihydrocamalexate synthase/camalexin synthase
Synonym PAD3
EC number EC 1.14.19.52
Entrez Gene 822298
Refseq mrna NM_113595
Refseq protein NP_189318
Function Multifunctional enzyme involved in the biosynthesis of the indole-derived phytoalexin camalexin. Catalyzes two reactions, the formation of dihydrocamalexate from indole-3-acetonitrile-cysteine conjugate and the oxidative decarboxylation of dihydrocamalexate which is the final step in camalexin biosynthesis (Ferrari et al. 2003)
Group Camalexin biosynthesis
Reference Zhou et al. (1999); Ferrari et al. (2003); Bohman et al. (2003); Glawischnig (2006); Schuhegger et al. (2007); Schuhegger et al. (2006); Glawischnig (2007); Nafisi et al. (2007); Böttcher et al. (2009); Chapman et al. (2016); Liu et al. (2016); Savatin et
Organism AGI ID Gene Name Protein Name Identity E-Value Description

Papaya

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

44.018

8.39E-115

Papaya

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

41.913

1.19E-111

Papaya

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

43.049

5.96E-109

Papaya

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

43.177

1.81E-105

Papaya

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

44.165

2.20E-103

Papaya

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

40.359

1.28E-90

Papaya

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

45.872

6.02E-56

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

65.939

0

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

61.777

0

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

59.641

3.29E-179

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

53.472

3.95E-157

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

51.398

9.20E-157

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

54.176

2.53E-148

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

51.537

6.77E-143

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

51.448

2.12E-142

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

52.703

1.92E-140

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

49.548

6.95E-138

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

51.044

2.28E-137

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

48.552

2.72E-134

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

41.907

3.83E-110

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

41.256

5.59E-105

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

43.056

1.31E-104

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

49.855

6.13E-104

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

50.459

2.12E-103

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

44.318

2.78E-102

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

40.183

7.02E-102

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

40.271

1.20E-100

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

70.256

3.84E-84

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

50

2.86E-80

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

69.061

1.57E-73

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

65.294

2.72E-68

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

56.757

2.86E-65

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

59.777

6.85E-64

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

59.563

7.17E-62

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

57.843

8.94E-62

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

59.649

1.33E-61

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

58.201

8.84E-59

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

60

2.00E-58

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

50.254

2.33E-56

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

56.983

1.14E-54

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

73.729

4.76E-53

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

52.096

6.88E-51

Broccoli

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

53.254

1.67E-50

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

66.013

0

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

64.77

0

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

63.719

0

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

63.039

0

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

62.358

0

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

59.637

0

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

59.865

5.41E-180

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

58.575

4.24E-176

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

53.472

4.56E-157

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

51.818

4.15E-152

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

50.889

1.29E-150

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

52.5

1.11E-149

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

52.778

1.12E-149

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

50.797

3.36E-148

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

51.936

2.49E-147

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

51.693

4.94E-145

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

51.67

4.63E-144

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

48.312

2.49E-143

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

50.554

3.63E-142

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

50.465

4.13E-140

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

50.685

1.24E-139

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

48.869

2.39E-136

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

48.858

6.08E-136

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

51.016

8.64E-136

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

49.203

7.55E-135

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

49.886

1.49E-131

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

48.19

8.89E-129

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

46.17

5.06E-125

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

47.333

9.76E-123

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

41.907

5.92E-109

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

41.002

6.26E-105

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

41.23

1.80E-103

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

42.593

4.35E-103

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

42.334

9.75E-102

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

44.688

4.49E-78

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

44.599

4.43E-75

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

56.075

2.62E-69

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

53.304

5.16E-67

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

43.966

1.34E-55

Cabbage

AT3G26830

CYP71B15

Bifunctional dihydrocamalexate synthase/camalexin synthase

46.479

5.38E-52

GO ID Ontology GO Term Description

GO:0004497

MF

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

GO:0005506

MF

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

GO:0005783

CC

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisterna

GO:0006952

BP

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

GO:0009414

BP

response to water deprivation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009625

BP

response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.

GO:0009700

BP

indole phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.

GO:0009737

BP

response to abscisic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.

GO:0010112

BP

regulation of systemic acquired resistance

Any process that modulates the frequency, rate or extent of systemic acquired resistance.

GO:0010120

BP

camalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.

GO:0010298

MF

dihydrocamalexic acid decarboxylase activity

Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.

GO:0016020

CC

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

GO:0016021

CC

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

GO:0016709

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

GO:0019825

MF

oxygen binding

Interacting selectively and non-covalently with oxygen (O2).

GO:0020037

MF

heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

GO:0043231

CC

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0004497

MF

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

GO:0005506

MF

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

GO:0005783

CC

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisterna

GO:0006952

BP

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

GO:0009414

BP

response to water deprivation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009625

BP

response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.

GO:0009700

BP

indole phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.

GO:0009737

BP

response to abscisic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.

GO:0010112

BP

regulation of systemic acquired resistance

Any process that modulates the frequency, rate or extent of systemic acquired resistance.

GO:0010120

BP

camalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.

GO:0010298

MF

dihydrocamalexic acid decarboxylase activity

Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.

GO:0016020

CC

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

GO:0016021

CC

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

GO:0016709

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

GO:0019825

MF

oxygen binding

Interacting selectively and non-covalently with oxygen (O2).

GO:0020037

MF

heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

GO:0043231

CC

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0004497

MF

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

GO:0005506

MF

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

GO:0005783

CC

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisterna

GO:0006952

BP

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

GO:0009414

BP

response to water deprivation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009625

BP

response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.

GO:0009700

BP

indole phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.

GO:0009737

BP

response to abscisic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.

GO:0010112

BP

regulation of systemic acquired resistance

Any process that modulates the frequency, rate or extent of systemic acquired resistance.

GO:0010120

BP

camalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.

GO:0010298

MF

dihydrocamalexic acid decarboxylase activity

Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.

GO:0016020

CC

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

GO:0016021

CC

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

GO:0016709

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

GO:0019825

MF

oxygen binding

Interacting selectively and non-covalently with oxygen (O2).

GO:0020037

MF

heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

GO:0043231

CC

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0004497

MF

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

GO:0005506

MF

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

GO:0005783

CC

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisterna

GO:0006952

BP

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

GO:0009414

BP

response to water deprivation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009625

BP

response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.

GO:0009700

BP

indole phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.

GO:0009737

BP

response to abscisic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.

GO:0010112

BP

regulation of systemic acquired resistance

Any process that modulates the frequency, rate or extent of systemic acquired resistance.

GO:0010120

BP

camalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.

GO:0010298

MF

dihydrocamalexic acid decarboxylase activity

Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.

GO:0016020

CC

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

GO:0016021

CC

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

GO:0016709

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

GO:0019825

MF

oxygen binding

Interacting selectively and non-covalently with oxygen (O2).

GO:0020037

MF

heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

GO:0043231

CC

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0004497

MF

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

GO:0005506

MF

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

GO:0005783

CC

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisterna

GO:0006952

BP

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

GO:0009414

BP

response to water deprivation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009625

BP

response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.

GO:0009700

BP

indole phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.

GO:0009737

BP

response to abscisic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.

GO:0010112

BP

regulation of systemic acquired resistance

Any process that modulates the frequency, rate or extent of systemic acquired resistance.

GO:0010120

BP

camalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.

GO:0010298

MF

dihydrocamalexic acid decarboxylase activity

Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.

GO:0016020

CC

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

GO:0016021

CC

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

GO:0016709

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

GO:0019825

MF

oxygen binding

Interacting selectively and non-covalently with oxygen (O2).

GO:0020037

MF

heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

GO:0043231

CC

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0004497

MF

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

GO:0005506

MF

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

GO:0005783

CC

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisterna

GO:0006952

BP

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

GO:0009414

BP

response to water deprivation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009625

BP

response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.

GO:0009700

BP

indole phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.

GO:0009737

BP

response to abscisic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.

GO:0010112

BP

regulation of systemic acquired resistance

Any process that modulates the frequency, rate or extent of systemic acquired resistance.

GO:0010120

BP

camalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.

GO:0010298

MF

dihydrocamalexic acid decarboxylase activity

Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.

GO:0016020

CC

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

GO:0016021

CC

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

GO:0016709

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

GO:0019825

MF

oxygen binding

Interacting selectively and non-covalently with oxygen (O2).

GO:0020037

MF

heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

GO:0043231

CC

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0004497

MF

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

GO:0005506

MF

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

GO:0005783

CC

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisterna

GO:0006952

BP

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

GO:0009414

BP

response to water deprivation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009625

BP

response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.

GO:0009700

BP

indole phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.

GO:0009737

BP

response to abscisic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.

GO:0010112

BP

regulation of systemic acquired resistance

Any process that modulates the frequency, rate or extent of systemic acquired resistance.

GO:0010120

BP

camalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.

GO:0010298

MF

dihydrocamalexic acid decarboxylase activity

Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.

GO:0016020

CC

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

GO:0016021

CC

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

GO:0016709

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

GO:0019825

MF

oxygen binding

Interacting selectively and non-covalently with oxygen (O2).

GO:0020037

MF

heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

GO:0043231

CC

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0004497

MF

monooxygenase activity

Catalysis of the incorporation of one atom from molecular oxygen into a compound and the reduction of the other atom of oxygen to water.

GO:0005506

MF

iron ion binding

Interacting selectively and non-covalently with iron (Fe) ions.

GO:0005783

CC

endoplasmic reticulum

The irregular network of unit membranes, visible only by electron microscopy, that occurs in the cytoplasm of many eukaryotic cells. The membranes form a complex meshwork of tubular channels, which are often expanded into slitlike cavities called cisterna

GO:0006952

BP

defense response

Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.

GO:0009414

BP

response to water deprivation

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009625

BP

response to insect

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from an insect.

GO:0009700

BP

indole phytoalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of indole phytoalexins, any indole compound produced by plants as part of their defense response.

GO:0009737

BP

response to abscisic acid

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.

GO:0010112

BP

regulation of systemic acquired resistance

Any process that modulates the frequency, rate or extent of systemic acquired resistance.

GO:0010120

BP

camalexin biosynthetic process

The chemical reactions and pathways resulting in the formation of camalexin, an indole phytoalexin.

GO:0010298

MF

dihydrocamalexic acid decarboxylase activity

Catalysis of the reaction: dihydrocamalexic acid = camalexin + CO2 + H+.

GO:0016020

CC

membrane

A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.

GO:0016021

CC

integral component of membrane

The component of a membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.

GO:0016709

MF

oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen

Catalysis of an oxidation-reduction (redox) reaction in which hydrogen or electrons are transferred from NADH or NADPH and one other donor, and one atom of oxygen is incorporated into one donor.

GO:0019825

MF

oxygen binding

Interacting selectively and non-covalently with oxygen (O2).

GO:0020037

MF

heme binding

Interacting selectively and non-covalently with heme, any compound of iron complexed in a porphyrin (tetrapyrrole) ring.

GO:0043231

CC

intracellular membrane-bounded organelle

Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

Pubmed ID Authors Year Title Journal Description

26795461

Chapman, A., Lindermayr, C. and Glawischnig, E.

2016

Expression of antimicrobial peptides under control of a camalexin-biosynthetic promoter confers enhanced resistance against Pseudomonas syringae.

Phytochemistry

26973671

Liu, S., Bartnikas, L.M., Volko, S.M., Ausubel, F.M. and Tang, D.

2016

Mutation of the Glucosinolate Biosynthesis Enzyme Cytochrome P450 83A1 Monooxygenase Increases Camalexin Accumulation and Powdery Mildew Resistance.

Front Plant Sci

29085857

Savatin, D.V., Bisceglia, N.G., Gravino, M., Fabbri, C., Pontiggia, D. and Mattei, B.

2015

Camalexin Quantification in Arabidopsis thaliana Leaves Infected with Botrytis cinerea.

Bio Protoc

26257750

Lemarié, S., Robert-Seilaniantz, A., Lariagon, C., Lemoine, J., Marnet, N., Levrel, A., Jubault, M., Manzanares-Dauleux, M.J. and Gravot, A.

2015

Camalexin contributes to the partial resistance of Arabidopsis thaliana to the biotrophic soilborne protist Plasmodiophora brassicae.

Front Plant Sci

26379682

Frerigmann, H., Glawischnig, E. and Gigolashvili, T.

2015

The role of MYB34, MYB51 and MYB122 in the regulation of camalexin biosynthesis in Arabidopsis thaliana.

Front Plant Sci

25236170

Cargnel, M.D., Demkura, P.V. and Ballaré, C.L.

2014

Linking phytochrome to plant immunity: low red : far-red ratios increase Arabidopsis susceptibility to Botrytis cinerea by reducing the biosynthesis of indolic glucosinolates and camalexin.

New Phytol

23528052

Kettles, G.J., Drurey, C., Schoonbeek, H.J., Maule, A.J. and Hogenhout, S.A.

2013

Resistance of Arabidopsis thaliana to the green peach aphid, Myzus persicae, involves camalexin and is regulated by microRNAs.

New Phytol

22870889

Zandalinas, S.I., Vives-Peris, V., Gómez-Cadenas, A. and Arbona, V.

2012

A fast and precise method to identify indolic glucosinolates and camalexin in plants by combining mass spectrometric and biological information.

J Agric Food Chem

22624950

Wang, M.Y., Liu, X.T., Chen, Y., Xu, X.J., Yu, B., Zhang, S.Q., Li, Q. and He, Z.H.

2012

Arabidopsis acetyl-amido synthetase GH3.5 involvement in camalexin biosynthesis through conjugation of indole-3-carboxylic acid and cysteine and upregulation of camalexin biosynthesis genes.

J Integr Plant Biol

22295908

Saga, H., Ogawa, T., Kai, K., Suzuki, H., Ogata, Y., Sakurai, N., Shibata, D. and Ohta, D.

2012

Identification and characterization of ANAC042, a transcription factor family gene involved in the regulation of camalexin biosynthesis in Arabidopsis.

Mol Plant Microbe Interact

21239642

Su, T., Xu, J., Li, Y., Lei, L., Zhao, L., Yang, H., Feng, J., Liu, G. and Ren, D.

2011

Glutathione-indole-3-acetonitrile is required for camalexin biosynthesis in Arabidopsis thaliana.

Plant Cell

19220763

Persson, M., Staal, J., Oide, S. and Dixelius, C.

2009

Layers of defense responses to Leptosphaeria maculans below the RLM1- and camalexin-dependent resistances.

New Phytol

19154205

Stefanato, F.L., Abou‐Mansour, E., Buchala, A., Kretschmer, M., Mosbach, A., Hahn, M., Bochet, C.G., Métraux, J.P. and Schoonbeek, H.J.

2009

The ABC transporter BcatrB from Botrytis cinerea exports camalexin and is a virulence factor on Arabidopsis thaliana.

Plant J

19567706

Böttcher, C., Westphal, L., Schmotz, C., Prade, E., Scheel, D. and Glawischnig, E.

2009

The multifunctional enzyme CYP71B15 (PHYTOALEXIN DEFICIENT3) converts cysteine-indole-3-acetonitrile to camalexin in the indole-3-acetonitrile metabolic network of Arabidopsis thaliana.

Plant Cell

17573535

Nafisi, M., Goregaoker, S., Botanga, C.J., Glawischnig, E., Olsen, C.E., Halkier, B.A. and Glazebrook, J.

2007

Arabidopsis cytochrome P450 monooxygenase 71A13 catalyzes the conversion of indole-3-acetaldoxime in camalexin synthesis.

Plant Cell

17217970

Glawischnig, E.

2007

Camalexin.

Phytochemistry

16766671

Schuhegger, R., Nafisi, M., Mansourova, M., Petersen, B.L., Olsen, C.E., Svatoš, A., Halkier, B.A. and Glawischnig, E.

2006

CYP71B15 (PAD3) catalyzes the final step in camalexin biosynthesis.

Plant Physiol

16769150

Schuhegger, R., Rauhut, T. and Glawischnig, E.

2007

Regulatory variability of camalexin biosynthesis.

J Plant Physiol

17073786

Glawischnig, E.

2006

The role of cytochrome P450 enzymes in the biosynthesis of camalexin.

Biochem Soc Trans

14675428

Bohman, S., Staal, J., Thomma, B.P., Wang, M. and Dixelius, C.

2003

Characterisation of an Arabidopsis–Leptosphaeria maculans pathosystem: resistance partially requires camalexin biosynthesis and is independent of salicylic acid, ethylene and jasmonic acid signalling

The Plant Journal

12848825

Ferrari, S., Plotnikova, J.M., De Lorenzo, G. and Ausubel, F.M.

2003

Arabidopsis local resistance to Botrytis cinerea involves salicylic acid and camalexin and requires EDS4 and PAD2, but not SID2, EDS5 or PAD4

The Plant Journal

10590168

Zhou, N., Tootle, T.L. and Glazebrook, J.

1999

Arabidopsis PAD3, a gene required for camalexin biosynthesis, encodes a putative cytochrome P450 monooxygenase.

The Plant Cell