SuCComBase

Sulfur Containing Compound Database

SCC Gene Description

Gene name GSTF11
AGI ID AT3G03190
Gene length 214
Uniprot ID Q96324
Protein Name Glutathione S-transferase F11
Synonym ATGSTF11
EC number EC 2.5.1.18
Entrez Gene 821227
Refseq mrna NM_111189
Refseq protein NP_186969
Function GST-type enzymes may be involved in an enzyme complex formed by CYP83s and C-S lyase. The S-alkylthiohydroximate formed after CYP83-catalyzed aldoxime oxidation and spontaneous conjugation to cysteine is cyclized in vitro to form a dead-end product. Hence metabolic channeling aided by GST-type enzymes is postulated in vivo to avoid this consequence the dead-end product. The two putative GST genes (At3g03190 and At1g78370) could be candidates coding for such an activity (Hirai et al. 2005)
Group GSL core structure synthesis
Reference Hirai et al. (2005); Hirai et al. (2007); Wentzell et al. (2007)
Organism AGI ID Gene Name Protein Name Identity E-Value Description

Cabbage

AT3G03190

GSTF11

Glutathione S-transferase F11

80

3.00E-125

Broccoli

AT3G03190

GSTF11

Glutathione S-transferase F11

71

2.00E-114

Cabbage

AT3G03190

GSTF11

Glutathione S-transferase F11

70

1.00E-113

Broccoli

AT3G03190

GSTF11

Glutathione S-transferase F11

69

3.00E-112

Cabbage

AT3G03190

GSTF11

Glutathione S-transferase F11

70

8.00E-112

Papaya

AT3G03190

GSTF11

Glutathione S-transferase F11

61

2.00E-94

Papaya

AT3G03190

GSTF11

Glutathione S-transferase F11

49

4.00E-69

Cabbage

AT3G03190

GSTF11

Glutathione S-transferase F11

46

4.00E-63

Broccoli

AT3G03190

GSTF11

Glutathione S-transferase F11

46

9.00E-63

Broccoli

AT3G03190

GSTF11

Glutathione S-transferase F11

45

4.00E-62

Cabbage

AT3G03190

GSTF11

Glutathione S-transferase F11

45

5.00E-62

Papaya

AT3G03190

GSTF11

Glutathione S-transferase F11

45

2.00E-61

Broccoli

AT3G03190

GSTF11

Glutathione S-transferase F11

43

2.00E-60

Broccoli

AT3G03190

GSTF11

Glutathione S-transferase F11

47

4.00E-56

Broccoli

AT3G03190

GSTF11

Glutathione S-transferase F11

46

4.00E-55

Broccoli

AT3G03190

GSTF11

Glutathione S-transferase F11

45

2.00E-54

Broccoli

AT3G03190

GSTF11

Glutathione S-transferase F11

44

1.00E-51

Papaya

AT3G03190

GSTF11

Glutathione S-transferase F11

44

1.00E-51

GO ID Ontology GO Term Description

GO:0004364

MF

glutathione transferase activity

Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.

GO:0005737

CC

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0006749

BP

glutathione metabolic process

The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific rol

GO:0006979

BP

response to oxidative stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactiv

GO:0009407

BP

toxin catabolic process

The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

GO:0004364

MF

glutathione transferase activity

Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.

GO:0005737

CC

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0006749

BP

glutathione metabolic process

The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific rol

GO:0006979

BP

response to oxidative stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactiv

GO:0009407

BP

toxin catabolic process

The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

GO:0004364

MF

glutathione transferase activity

Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.

GO:0005737

CC

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0006749

BP

glutathione metabolic process

The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific rol

GO:0006979

BP

response to oxidative stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactiv

GO:0009407

BP

toxin catabolic process

The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

GO:0004364

MF

glutathione transferase activity

Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.

GO:0005737

CC

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0006749

BP

glutathione metabolic process

The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific rol

GO:0006979

BP

response to oxidative stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactiv

GO:0009407

BP

toxin catabolic process

The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

GO:0004364

MF

glutathione transferase activity

Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.

GO:0005737

CC

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0006749

BP

glutathione metabolic process

The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific rol

GO:0006979

BP

response to oxidative stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactiv

GO:0009407

BP

toxin catabolic process

The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

GO:0004364

MF

glutathione transferase activity

Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.

GO:0005737

CC

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0006749

BP

glutathione metabolic process

The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific rol

GO:0006979

BP

response to oxidative stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactiv

GO:0009407

BP

toxin catabolic process

The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

GO:0004364

MF

glutathione transferase activity

Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.

GO:0005737

CC

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0006749

BP

glutathione metabolic process

The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific rol

GO:0006979

BP

response to oxidative stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactiv

GO:0009407

BP

toxin catabolic process

The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

GO:0004364

MF

glutathione transferase activity

Catalysis of the reaction: R-X + glutathione = H-X + R-S-glutathione. R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group.

GO:0005737

CC

cytoplasm

All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0006749

BP

glutathione metabolic process

The chemical reactions and pathways involving glutathione, the tripeptide glutamylcysteinylglycine, which acts as a coenzyme for some enzymes and as an antioxidant in the protection of sulfhydryl groups in enzymes and other proteins; it has a specific rol

GO:0006979

BP

response to oxidative stress

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactiv

GO:0009407

BP

toxin catabolic process

The chemical reactions and pathways resulting in the breakdown of toxin, a poisonous compound (typically a protein) that is produced by cells or organisms and that can cause disease when introduced into the body or tissues of an organism.

Pubmed ID Authors Year Title Journal Description

15866872

Hirai, M.Y., Klein, M., Fujikawa, Y., Yano, M., Goodenowe, D.B., Yamazaki, Y., Kanaya, S., Nakamura, Y., Kitayama, M., Suzuki, H., Sakurai, N., Shibata, D., Tokuhisa, J., Reichelt, M., Gershenzon, J., Papenbrock, J. & Saito, K.

2005

Elucidation of gene-to-gene and metabolite-to-gene networks in arabidopsis by integration of metabolomics and transcriptomics

J Biol Chem

17420480

Hirai, M.Y., Sugiyama, K., Sawada, Y., Tohge, T., Obayashi, T., Suzuki, A., Araki, R., Sakurai, N., Suzuki, H., Aoki, K., Goda, H. & Nishizawa, O.I.

2007

Omics-based identification of Arabidopsis Myb transcription factors regulating aliphatic glucosinolate biosynthesis

Proc Natl Acad Sci U S A

17941713

Wentzell, A.M., Rowe, H.C., Hansen, B.G., Ticconi, C., Halkier, B.A. & Kliebenstein, D.J.

2007

Linking metabolic QTLs with network and cis-eQTLs controlling biosynthetic pathways

PLoS Genet