SuCComBase

Sulfur Containing Compound Database

SCC Gene Description

Gene name APK1
AGI ID AT2G14750
Gene length 276
Uniprot ID Q43295
Protein Name Adenylyl-sulfate kinase 1 chloroplastic
Synonym ATAKN1
EC number EC 2.7.1.25
Entrez Gene 815963
Refseq mrna NM_127039
Refseq protein NP_179082
Function The levels of GSLs and the sulfated 12-hydroxyjasmonate were reduced approximately fivefold in apk1 apk2 plants. The reduction in GSLs resulted in increased transcript levels for genes involved in GSL biosynthesis and accumulation of desulfated precursors (Mugford et al. 2009)
Group GSL core structure synthesis
Reference Badenes-Perez et al. (2013); Mugford et al. (2009); Kopriva et al. (2009)
Organism AGI ID Gene Name Protein Name Identity E-Value Description

Broccoli

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

86

3.00E-171

Cabbage

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

85

2.00E-169

Broccoli

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

85

6.00E-167

Cabbage

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

85

2.00E-166

Papaya

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

75

7.00E-115

Papaya

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

77

1.00E-114

Cabbage

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

73

3.00E-113

Broccoli

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

77

5.00E-113

Cabbage

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

77

1.00E-112

Cabbage

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

77

2.00E-112

Broccoli

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

76

1.00E-111

Cabbage

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

78

8.00E-111

Broccoli

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

71

5.00E-107

Broccoli

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

71

5.00E-107

Papaya

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

82

2.00E-101

Papaya

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

76

8.00E-99

Cabbage

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

68

2.00E-85

Broccoli

AT2G14750

APK1

Adenylyl-sulfate kinase 1 chloroplastic

61

5.00E-79

GO ID Ontology GO Term Description

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004020

MF

adenylylsulfate kinase activity

Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0010439

BP

regulation of glucosinolate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0016301

MF

kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

GO:0016310

BP

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

GO:0016772

MF

transferase activity, transferring phosphorus-containing groups

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0042802

MF

identical protein binding

Interacting selectively and non-covalently with an identical protein or proteins.

GO:0048232

BP

male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.

GO:0070814

BP

hydrogen sulfide biosynthetic process

The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004020

MF

adenylylsulfate kinase activity

Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0010439

BP

regulation of glucosinolate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0016301

MF

kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

GO:0016310

BP

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

GO:0016772

MF

transferase activity, transferring phosphorus-containing groups

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0042802

MF

identical protein binding

Interacting selectively and non-covalently with an identical protein or proteins.

GO:0048232

BP

male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.

GO:0070814

BP

hydrogen sulfide biosynthetic process

The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004020

MF

adenylylsulfate kinase activity

Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0010439

BP

regulation of glucosinolate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0016301

MF

kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

GO:0016310

BP

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

GO:0016772

MF

transferase activity, transferring phosphorus-containing groups

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0042802

MF

identical protein binding

Interacting selectively and non-covalently with an identical protein or proteins.

GO:0048232

BP

male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.

GO:0070814

BP

hydrogen sulfide biosynthetic process

The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004020

MF

adenylylsulfate kinase activity

Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0010439

BP

regulation of glucosinolate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0016301

MF

kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

GO:0016310

BP

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

GO:0016772

MF

transferase activity, transferring phosphorus-containing groups

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0042802

MF

identical protein binding

Interacting selectively and non-covalently with an identical protein or proteins.

GO:0048232

BP

male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.

GO:0070814

BP

hydrogen sulfide biosynthetic process

The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004020

MF

adenylylsulfate kinase activity

Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0010439

BP

regulation of glucosinolate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0016301

MF

kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

GO:0016310

BP

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

GO:0016772

MF

transferase activity, transferring phosphorus-containing groups

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0042802

MF

identical protein binding

Interacting selectively and non-covalently with an identical protein or proteins.

GO:0048232

BP

male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.

GO:0070814

BP

hydrogen sulfide biosynthetic process

The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004020

MF

adenylylsulfate kinase activity

Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0010439

BP

regulation of glucosinolate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0016301

MF

kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

GO:0016310

BP

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

GO:0016772

MF

transferase activity, transferring phosphorus-containing groups

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0042802

MF

identical protein binding

Interacting selectively and non-covalently with an identical protein or proteins.

GO:0048232

BP

male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.

GO:0070814

BP

hydrogen sulfide biosynthetic process

The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004020

MF

adenylylsulfate kinase activity

Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0010439

BP

regulation of glucosinolate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0016301

MF

kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

GO:0016310

BP

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

GO:0016772

MF

transferase activity, transferring phosphorus-containing groups

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0042802

MF

identical protein binding

Interacting selectively and non-covalently with an identical protein or proteins.

GO:0048232

BP

male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.

GO:0070814

BP

hydrogen sulfide biosynthetic process

The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004020

MF

adenylylsulfate kinase activity

Catalysis of the reaction: ATP + adenylylsulfate = ADP + 3'-phosphoadenosine 5'-phosphosulfate.

GO:0005524

MF

ATP binding

Interacting selectively and non-covalently with ATP, adenosine 5'-triphosphate, a universally important coenzyme and enzyme regulator.

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0010439

BP

regulation of glucosinolate biosynthetic process

Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae.

GO:0016301

MF

kinase activity

Catalysis of the transfer of a phosphate group, usually from ATP, to a substrate molecule.

GO:0016310

BP

phosphorylation

The process of introducing a phosphate group into a molecule, usually with the formation of a phosphoric ester, a phosphoric anhydride or a phosphoric amide.

GO:0016772

MF

transferase activity, transferring phosphorus-containing groups

Catalysis of the transfer of a phosphorus-containing group from one compound (donor) to another (acceptor).

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0042802

MF

identical protein binding

Interacting selectively and non-covalently with an identical protein or proteins.

GO:0048232

BP

male gamete generation

Generation of the male gamete; specialised haploid cells produced by meiosis and along with a female gamete takes part in sexual reproduction.

GO:0070814

BP

hydrogen sulfide biosynthetic process

The chemical reactions and pathways resulting in the formation of hydrogen sulfide, H2S.

Pubmed ID Authors Year Title Journal Description

23218016

Badenes-Perez, F.R., Reichelt, M., Gershenzon, J. & Heckel, D.G.

2013

Interaction of glucosinolate content of Arabidopsis thaliana mutant lines and feeding and oviposition by generalist and specialist lepidopterans

Phytochemistry

19304933

Mugford, S.G., Yoshimoto, N., Reichelt, M., Wirtz, M., Hill, L., Mugford, S.T., Noji, M., Takahashi, H., Kramell, R., Gigolashvili, T., Flu, U., Saito, K., Kopriva, S. & Gershenzon, J.

2009

Disruption of adenosine-5'-phosphosulfate kinase in Arabidopsis reduces levels of sulfated secondary metabolites

Plant Cell

22833750

Kopriva, S., Mugford, S.G., Baraniecka, P., Lee, B.R., Matthewman, C.A. & Koprivova, A.

2012

Control of sulfur partitioning between primary and secondary metabolism in Arabidopsis

Front Plant Sci