SuCComBase

Sulfur Containing Compound Database

SCC Gene Description

Gene name ICS1
AGI ID AT1G74710
Gene length 524
Uniprot ID Q9S7H8
Protein Name Isochorismate synthase 1, chloroplastic
Synonym EDS16
EC number EC 5.4.4.2
Entrez Gene 843810
Refseq mrna NM_106129
Refseq protein NP_565090
Function Decreasing camalexin levels by mutation of the camalexin synthetase gene PAD3 or the camalexin synthesis regulator AtWRKY33 compromised the powdery mildew resistance in these mutants (Liu et al. 2016)
Group Camalexin biosynthesis
Reference Liu et al. (2016)
Organism AGI ID Gene Name Protein Name Identity E-Value Description

Papaya

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

59.002

0

Broccoli

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

84.341

0

Broccoli

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

76.245

0

Broccoli

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

91.667

1.78E-179

Broccoli

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

71.098

1.53E-159

Broccoli

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

79.866

1.99E-75

Broccoli

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

92.553

2.96E-51

Cabbage

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

88.811

0

Cabbage

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

87.587

0

Cabbage

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

86.116

0

Cabbage

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

77.395

0

Cabbage

AT1G74710

ICS1

Isochorismate synthase 1, chloroplastic

75.958

0

GO ID Ontology GO Term Description

GO:0008909

MF

isochorismate synthase activity

Catalysis of the reaction: chorismate = isochorismate.

GO:0009409

BP

response to cold

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that or

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009627

BP

systemic acquired resistance

The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.

GO:0009697

BP

salicylic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.

GO:0010118

BP

stomatal movement

The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).

GO:0031348

BP

negative regulation of defense response

Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.

GO:0042372

BP

phylloquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.

GO:0042742

BP

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

GO:0046654

BP

tetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

GO:0046820

MF

4-amino-4-deoxychorismate synthase activity

Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, re

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0008909

MF

isochorismate synthase activity

Catalysis of the reaction: chorismate = isochorismate.

GO:0009409

BP

response to cold

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that or

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009627

BP

systemic acquired resistance

The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.

GO:0009697

BP

salicylic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.

GO:0010118

BP

stomatal movement

The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).

GO:0031348

BP

negative regulation of defense response

Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.

GO:0042372

BP

phylloquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.

GO:0042742

BP

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

GO:0046654

BP

tetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

GO:0046820

MF

4-amino-4-deoxychorismate synthase activity

Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, re

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0008909

MF

isochorismate synthase activity

Catalysis of the reaction: chorismate = isochorismate.

GO:0009409

BP

response to cold

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that or

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009627

BP

systemic acquired resistance

The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.

GO:0009697

BP

salicylic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.

GO:0010118

BP

stomatal movement

The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).

GO:0031348

BP

negative regulation of defense response

Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.

GO:0042372

BP

phylloquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.

GO:0042742

BP

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

GO:0046654

BP

tetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

GO:0046820

MF

4-amino-4-deoxychorismate synthase activity

Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, re

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0008909

MF

isochorismate synthase activity

Catalysis of the reaction: chorismate = isochorismate.

GO:0009409

BP

response to cold

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that or

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009627

BP

systemic acquired resistance

The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.

GO:0009697

BP

salicylic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.

GO:0010118

BP

stomatal movement

The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).

GO:0031348

BP

negative regulation of defense response

Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.

GO:0042372

BP

phylloquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.

GO:0042742

BP

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

GO:0046654

BP

tetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

GO:0046820

MF

4-amino-4-deoxychorismate synthase activity

Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, re

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0008909

MF

isochorismate synthase activity

Catalysis of the reaction: chorismate = isochorismate.

GO:0009409

BP

response to cold

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that or

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009627

BP

systemic acquired resistance

The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.

GO:0009697

BP

salicylic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.

GO:0010118

BP

stomatal movement

The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).

GO:0031348

BP

negative regulation of defense response

Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.

GO:0042372

BP

phylloquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.

GO:0042742

BP

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

GO:0046654

BP

tetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

GO:0046820

MF

4-amino-4-deoxychorismate synthase activity

Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, re

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0008909

MF

isochorismate synthase activity

Catalysis of the reaction: chorismate = isochorismate.

GO:0009409

BP

response to cold

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that or

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009627

BP

systemic acquired resistance

The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.

GO:0009697

BP

salicylic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.

GO:0010118

BP

stomatal movement

The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).

GO:0031348

BP

negative regulation of defense response

Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.

GO:0042372

BP

phylloquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.

GO:0042742

BP

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

GO:0046654

BP

tetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

GO:0046820

MF

4-amino-4-deoxychorismate synthase activity

Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, re

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0008909

MF

isochorismate synthase activity

Catalysis of the reaction: chorismate = isochorismate.

GO:0009409

BP

response to cold

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that or

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009627

BP

systemic acquired resistance

The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.

GO:0009697

BP

salicylic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.

GO:0010118

BP

stomatal movement

The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).

GO:0031348

BP

negative regulation of defense response

Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.

GO:0042372

BP

phylloquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.

GO:0042742

BP

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

GO:0046654

BP

tetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

GO:0046820

MF

4-amino-4-deoxychorismate synthase activity

Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, re

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

GO:0008909

MF

isochorismate synthase activity

Catalysis of the reaction: chorismate = isochorismate.

GO:0009409

BP

response to cold

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cold stimulus, a temperature stimulus below the optimal temperature for that or

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009536

CC

plastid

Any member of a family of organelles found in the cytoplasm of plants and some protists, which are membrane-bounded and contain DNA. Plant plastids develop from a common type, the proplastid.

GO:0009617

BP

response to bacterium

Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.

GO:0009627

BP

systemic acquired resistance

The salicylic acid mediated response to a pathogen which confers broad spectrum resistance.

GO:0009697

BP

salicylic acid biosynthetic process

The chemical reactions and pathways resulting in the formation of salicylic acid (2-hydroxybenzoic acid), a derivative of benzoic acid.

GO:0010118

BP

stomatal movement

The process of opening or closing of stomata, which is directly related to the stomatal conductance (measuring rate of passage of either water vapor or carbon dioxide (CO2) through stomata).

GO:0031348

BP

negative regulation of defense response

Any process that stops, prevents, or reduces the frequency, rate or extent of a defense response.

GO:0042372

BP

phylloquinone biosynthetic process

The chemical reactions and pathways resulting in the formation of phylloquinone, vitamin K1, a quinone-derived compound synthesized by green plants.

GO:0042742

BP

defense response to bacterium

Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.

GO:0046654

BP

tetrahydrofolate biosynthetic process

The chemical reactions and pathways resulting in the formation of tetrahydrofolate, 5,6,7,8-tetrahydrofolic acid, a folate derivative bearing additional hydrogens on the pterin group.

GO:0046820

MF

4-amino-4-deoxychorismate synthase activity

Catalysis of the reaction: L-glutamine + chorismate = 4-amino-4-deoxychorismate + L-glutamate. It is composed of two enzymatic activities (which may be present on one or two polypeptides); the first is a glutaminase which yields ammonia from glutamine, re

GO:0050832

BP

defense response to fungus

Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.

Pubmed ID Authors Year Title Journal Description

26973671

Liu, S., Bartnikas, L.M., Volko, S.M., Ausubel, F.M. and Tang, D.

2016

Mutation of the Glucosinolate Biosynthesis Enzyme Cytochrome P450 83A1 Monooxygenase Increases Camalexin Accumulation and Powdery Mildew Resistance.

Front Plant Sci