SuCComBase

Sulfur Containing Compound Database

SCC Gene Description

Gene name APR2
AGI ID AT1G62180
Gene length 454
Uniprot ID P92981
Protein Name 5'-adenylylsulfate reductase 2 chloroplastic
Synonym PRH43
EC number EC 1.8.4.9
Entrez Gene 842514
Refseq mrna NM_104899
Refseq protein NP_176409
Function Using trans-activation assays two isoforms of APK; APK1 and APK2 are regulated by both classes of GSL MYB transcription factors; whereas two ATPS genes; ATPS1 and ATPS3 are differentially regulated by these two groups of MYB factors. The adenosine 5-phosphosulfate reductases APR1; APR2; and APR3 which participate in primary sulfate reduction are also activated by the MYB factors (Yatusevich et al. 2010)
Group GSL core structure synthesis
Reference Yatusevich et al. (2010)
Organism AGI ID Gene Name Protein Name Identity E-Value Description

Cabbage

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

89

0.00E+00

Papaya

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

80

0.00E+00

Cabbage

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

76

0.00E+00

Broccoli

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

77

0.00E+00

Cabbage

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

76

0.00E+00

Cabbage

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

76

0.00E+00

Broccoli

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

76

0.00E+00

Broccoli

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

77

0.00E+00

Cabbage

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

77

0.00E+00

Papaya

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

72

0.00E+00

Papaya

AT1G62180

APR2

5'-adenylylsulfate reductase 2 chloroplastic

68

0.00E+00

GO ID Ontology GO Term Description

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004604

MF

phosphoadenylyl-sulfate reductase (thioredoxin) activity

Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009570

CC

chloroplast stroma

The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.

GO:0009973

MF

adenylyl-sulfate reductase activity

Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.

GO:0016671

MF

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0019379

BP

sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).

GO:0019419

BP

sulfate reduction

The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.

GO:0033741

MF

adenylyl-sulfate reductase (glutathione) activity

Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.

GO:0045454

BP

cell redox homeostasis

Any process that maintains the redox environment of a cell or compartment within a cell.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004604

MF

phosphoadenylyl-sulfate reductase (thioredoxin) activity

Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009570

CC

chloroplast stroma

The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.

GO:0009973

MF

adenylyl-sulfate reductase activity

Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.

GO:0016671

MF

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0019379

BP

sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).

GO:0019419

BP

sulfate reduction

The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.

GO:0033741

MF

adenylyl-sulfate reductase (glutathione) activity

Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.

GO:0045454

BP

cell redox homeostasis

Any process that maintains the redox environment of a cell or compartment within a cell.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004604

MF

phosphoadenylyl-sulfate reductase (thioredoxin) activity

Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009570

CC

chloroplast stroma

The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.

GO:0009973

MF

adenylyl-sulfate reductase activity

Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.

GO:0016671

MF

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0019379

BP

sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).

GO:0019419

BP

sulfate reduction

The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.

GO:0033741

MF

adenylyl-sulfate reductase (glutathione) activity

Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.

GO:0045454

BP

cell redox homeostasis

Any process that maintains the redox environment of a cell or compartment within a cell.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004604

MF

phosphoadenylyl-sulfate reductase (thioredoxin) activity

Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009570

CC

chloroplast stroma

The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.

GO:0009973

MF

adenylyl-sulfate reductase activity

Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.

GO:0016671

MF

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0019379

BP

sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).

GO:0019419

BP

sulfate reduction

The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.

GO:0033741

MF

adenylyl-sulfate reductase (glutathione) activity

Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.

GO:0045454

BP

cell redox homeostasis

Any process that maintains the redox environment of a cell or compartment within a cell.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004604

MF

phosphoadenylyl-sulfate reductase (thioredoxin) activity

Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009570

CC

chloroplast stroma

The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.

GO:0009973

MF

adenylyl-sulfate reductase activity

Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.

GO:0016671

MF

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0019379

BP

sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).

GO:0019419

BP

sulfate reduction

The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.

GO:0033741

MF

adenylyl-sulfate reductase (glutathione) activity

Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.

GO:0045454

BP

cell redox homeostasis

Any process that maintains the redox environment of a cell or compartment within a cell.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004604

MF

phosphoadenylyl-sulfate reductase (thioredoxin) activity

Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009570

CC

chloroplast stroma

The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.

GO:0009973

MF

adenylyl-sulfate reductase activity

Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.

GO:0016671

MF

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0019379

BP

sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).

GO:0019419

BP

sulfate reduction

The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.

GO:0033741

MF

adenylyl-sulfate reductase (glutathione) activity

Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.

GO:0045454

BP

cell redox homeostasis

Any process that maintains the redox environment of a cell or compartment within a cell.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004604

MF

phosphoadenylyl-sulfate reductase (thioredoxin) activity

Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009570

CC

chloroplast stroma

The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.

GO:0009973

MF

adenylyl-sulfate reductase activity

Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.

GO:0016671

MF

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0019379

BP

sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).

GO:0019419

BP

sulfate reduction

The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.

GO:0033741

MF

adenylyl-sulfate reductase (glutathione) activity

Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.

GO:0045454

BP

cell redox homeostasis

Any process that maintains the redox environment of a cell or compartment within a cell.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

GO:0000103

BP

sulfate assimilation

The pathways by which inorganic sulfate is processed and incorporated into sulfated compounds.

GO:0004604

MF

phosphoadenylyl-sulfate reductase (thioredoxin) activity

Catalysis of the reaction: adenosine 3',5'-diphosphate + H(+) + sulfite + thioredoxin disulfide = 3'-phospho-5'-adenylyl sulfate + thioredoxin. Thioredoxin disulfide is the oxidized form of thioredoxin; 3'-phosphoadenosine 5'-phosphosulfate is also known

GO:0009507

CC

chloroplast

A chlorophyll-containing plastid with thylakoids organized into grana and frets, or stroma thylakoids, and embedded in a stroma.

GO:0009570

CC

chloroplast stroma

The space enclosed by the double membrane of a chloroplast but excluding the thylakoid space. It contains DNA, ribosomes and some temporary products of photosynthesis.

GO:0009973

MF

adenylyl-sulfate reductase activity

Catalysis of the reaction: AMP + sulfite + acceptor = adenylyl sulfate + reduced acceptor.

GO:0016671

MF

oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor

Catalysis of an oxidation-reduction (redox) reaction in which a sulfur-containing group acts as a hydrogen or electron donor and reduces disulfide.

GO:0019344

BP

cysteine biosynthetic process

The chemical reactions and pathways resulting in the formation of cysteine, 2-amino-3-mercaptopropanoic acid.

GO:0019379

BP

sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin)

The pathway by which inorganic sulfate is processed and incorporated into sulfated compounds, where the phosphoadenylyl sulfate reduction step is catalyzed by the enzyme phosphoadenylyl-sulfate reductase (thioredoxin) (EC:1.8.4.8).

GO:0019419

BP

sulfate reduction

The chemical reactions and pathways resulting in the reduction of sulfate to another sulfur-containing ion or compound such as hydrogen sulfide, adenosine-phosphosulfate (APS) or thiosulfate.

GO:0033741

MF

adenylyl-sulfate reductase (glutathione) activity

Catalysis of the reaction: AMP + glutathione disulfide + H(+) + sulfite = 5'-adenylyl sulfate + 2 glutathione.

GO:0045454

BP

cell redox homeostasis

Any process that maintains the redox environment of a cell or compartment within a cell.

GO:0055114

BP

oxidation-reduction process

A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.

Pubmed ID Authors Year Title Journal Description

20042022

Yatusevich, R., Mugford, S.G., Matthewman, C., Gigolashvili, T., Frerigmann, H., Delaney, S., Koprivova, A. & Flu, U.

2010

Genes of primary sulfate assimilation are part of the glucosinolate biosynthetic network in Arabidopsis thaliana

Plant Journal