SuCComBase

Sulfur Containing Compound Database

SCC Gene Description

Gene name IGMT1
AGI ID AT1G21100
Gene length 373
Uniprot ID Q9LPU5
Protein Name Indole glucosinolate O-methyltransferase 1
Synonym T22I11.7
EC number EC 2.1.1.-
Entrez Gene 838706
Refseq mrna NM_101964
Refseq protein NP_173534
Function Arabidopsis O-methyl-transferase genes were found to coexpressed with CYP81F genes are fairly specific for the biosynthesis of modified indole GSLs which are IGMT1 and IGMT2. IGMT1 and 2 form a small gene cluster of O-MT genes on Arabidopsis chromosome 1 (Pfalz et al. 2011)
Group GSL side chain modification
Reference Pfalz et al. (2011)
Organism AGI ID Gene Name Protein Name Identity E-Value Description

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

93

0.00E+00

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

93

0.00E+00

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

93

0.00E+00

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

93

0.00E+00

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

91

0.00E+00

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

90

0.00E+00

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

89

0.00E+00

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

74

0.00E+00

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

72

0.00E+00

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

74

0.00E+00

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

73

4.00E-177

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

79

9.00E-169

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

96

7.00E-138

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

57

5.00E-135

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

54

2.00E-127

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

54

3.00E-127

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

56

1.00E-126

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

53

1.00E-125

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

55

2.00E-124

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

57

3.00E-124

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

56

2.00E-123

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

54

6.00E-123

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

57

3.00E-118

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

51

1.00E-117

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

54

2.00E-116

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

52

2.00E-115

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

72

6.00E-115

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

50

2.00E-114

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

51

2.00E-105

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

52

5.00E-101

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

52

2.00E-100

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

48

1.00E-97

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

47

6.00E-97

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

46

4.00E-95

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

46

1.00E-94

Papaya

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

47

2.00E-94

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

46

2.00E-94

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

46

5.00E-94

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

53

1.00E-92

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

46

1.00E-91

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

46

1.00E-90

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

43

5.00E-87

Broccoli

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

63

9.00E-87

Cabbage

AT1G21100

IGMT1

Indole glucosinolate O-methyltransferase 1

45

4.00E-85

GO ID Ontology GO Term Description

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0008168

MF

methyltransferase activity

Catalysis of the transfer of a methyl group to an acceptor molecule.

GO:0008171

MF

O-methyltransferase activity

Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.

GO:0008757

MF

S-adenosylmethionine-dependent methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

GO:0019438

BP

aromatic compound biosynthetic process

The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.

GO:0032259

BP

methylation

The process in which a methyl group is covalently attached to a molecule.

GO:0042343

BP

indole glucosinolate metabolic process

The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances b

GO:0046983

MF

protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0008168

MF

methyltransferase activity

Catalysis of the transfer of a methyl group to an acceptor molecule.

GO:0008171

MF

O-methyltransferase activity

Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.

GO:0008757

MF

S-adenosylmethionine-dependent methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

GO:0019438

BP

aromatic compound biosynthetic process

The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.

GO:0032259

BP

methylation

The process in which a methyl group is covalently attached to a molecule.

GO:0042343

BP

indole glucosinolate metabolic process

The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances b

GO:0046983

MF

protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0008168

MF

methyltransferase activity

Catalysis of the transfer of a methyl group to an acceptor molecule.

GO:0008171

MF

O-methyltransferase activity

Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.

GO:0008757

MF

S-adenosylmethionine-dependent methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

GO:0019438

BP

aromatic compound biosynthetic process

The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.

GO:0032259

BP

methylation

The process in which a methyl group is covalently attached to a molecule.

GO:0042343

BP

indole glucosinolate metabolic process

The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances b

GO:0046983

MF

protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0008168

MF

methyltransferase activity

Catalysis of the transfer of a methyl group to an acceptor molecule.

GO:0008171

MF

O-methyltransferase activity

Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.

GO:0008757

MF

S-adenosylmethionine-dependent methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

GO:0019438

BP

aromatic compound biosynthetic process

The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.

GO:0032259

BP

methylation

The process in which a methyl group is covalently attached to a molecule.

GO:0042343

BP

indole glucosinolate metabolic process

The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances b

GO:0046983

MF

protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0008168

MF

methyltransferase activity

Catalysis of the transfer of a methyl group to an acceptor molecule.

GO:0008171

MF

O-methyltransferase activity

Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.

GO:0008757

MF

S-adenosylmethionine-dependent methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

GO:0019438

BP

aromatic compound biosynthetic process

The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.

GO:0032259

BP

methylation

The process in which a methyl group is covalently attached to a molecule.

GO:0042343

BP

indole glucosinolate metabolic process

The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances b

GO:0046983

MF

protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0008168

MF

methyltransferase activity

Catalysis of the transfer of a methyl group to an acceptor molecule.

GO:0008171

MF

O-methyltransferase activity

Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.

GO:0008757

MF

S-adenosylmethionine-dependent methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

GO:0019438

BP

aromatic compound biosynthetic process

The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.

GO:0032259

BP

methylation

The process in which a methyl group is covalently attached to a molecule.

GO:0042343

BP

indole glucosinolate metabolic process

The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances b

GO:0046983

MF

protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0008168

MF

methyltransferase activity

Catalysis of the transfer of a methyl group to an acceptor molecule.

GO:0008171

MF

O-methyltransferase activity

Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.

GO:0008757

MF

S-adenosylmethionine-dependent methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

GO:0019438

BP

aromatic compound biosynthetic process

The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.

GO:0032259

BP

methylation

The process in which a methyl group is covalently attached to a molecule.

GO:0042343

BP

indole glucosinolate metabolic process

The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances b

GO:0046983

MF

protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

GO:0005515

MF

protein binding

Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).

GO:0005634

CC

nucleus

A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some

GO:0005829

CC

cytosol

The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.

GO:0008168

MF

methyltransferase activity

Catalysis of the transfer of a methyl group to an acceptor molecule.

GO:0008171

MF

O-methyltransferase activity

Catalysis of the transfer of a methyl group to the oxygen atom of an acceptor molecule.

GO:0008757

MF

S-adenosylmethionine-dependent methyltransferase activity

Catalysis of the transfer of a methyl group from S-adenosyl-L-methionine to a substrate.

GO:0019438

BP

aromatic compound biosynthetic process

The chemical reactions and pathways resulting in the formation of aromatic compounds, any substance containing an aromatic carbon ring.

GO:0032259

BP

methylation

The process in which a methyl group is covalently attached to a molecule.

GO:0042343

BP

indole glucosinolate metabolic process

The chemical reactions and pathways resulting in the formation of indole glucosinolates. Glucosinolates are sulfur-containing compounds that have a common structure linked to an R group derived from tryptophan; indoles are biologically active substances b

GO:0046983

MF

protein dimerization activity

The formation of a protein dimer, a macromolecular structure consists of two noncovalently associated identical or nonidentical subunits.

Pubmed ID Authors Year Title Journal Description

21317374

Pfalz, M., Mikkelsen, M.D., Olsen, C.E., Halkier, B.A. & Kroymann, J.

2011

Metabolic engineering in Nicotiana benthamiana reveals key enzyme functions in Arabidopsis indole glucosinolate modification

Plant Cell